Generalized anxiety disorder

Generalized anxiety disorder is a chronic psychiatric disorder of the central nervous system characterized by persistent, excessive, and difficult-to-control worry and apprehension regarding everyday activities and events

Generalized anxiety disorder is a chronic psychiatric disorder of the central nervous system characterized by persistent, excessive, and difficult-to-control worry and apprehension regarding everyday activities and events

Generalized anxiety disorder is a chronic psychiatric disorder of the central nervous system characterized by persistent, excessive, and difficult-to-control worry and apprehension regarding everyday activities and events Pathophysiologically, it involves altered functional connectivity and heightened activity within the amygdala, prefrontal cortex, and frontolimbic circuits, along with dysregulation of neurotransmitter systems including gamma-aminobutyric acid, serotonin, and norepinephrine

Pathophysiologically, it involves altered functional connectivity and heightened activity within the amygdala, prefrontal cortex, and frontolimbic circuits, along with dysregulation of neurotransmitter systems including gamma-aminobutyric acid, serotonin, and norepinephrine

Clinically, this pervasive worry persists for at least six months and is accompanied by somatic and autonomic symptoms such as muscle tension, motor restlessness, easy fatigability, difficulty concentrating, irritability, and sleep disturbances, leading to significant functional impairment

Clinically, this pervasive worry persists for at least six months and is accompanied by somatic and autonomic symptoms such as muscle tension, motor restlessness, easy fatigability, difficulty concentrating, irritability, and sleep disturbances, leading to significant functional impairment