Gingivostomatitis

Gingivostomatitis is an acute inflammatory and infectious disorder of the oral cavity involving both the gingiva and the broader oral mucosal surfaces Most frequently diagnosed in children under the age of five but capable of affecting individuals of any age, it is predominantly caused by primary infection with herpes simplex virus type 1, though it can also stem from other viral, bacterial, or coxsackievirus pathogens

Gingivostomatitis is an acute inflammatory and infectious disorder of the oral cavity involving both the gingiva and the broader oral mucosal surfaces Most frequently diagnosed in children under the age of five but capable of affecting individuals of any age, it is predominantly caused by primary infection with herpes simplex virus type 1, though it can also stem from other viral, bacterial, or coxsackievirus pathogens The condition is clinically characterized by a systemic prodrome of high feve...

The condition is clinically characterized by a systemic prodrome of high fever, irritability, and cervical lymphadenopathy, followed by widespread marginal gingival erythema, edema, and mucosal vesicles that rapidly ulcerate

Pathophysiologically, local viral invasion and replication within mucosal epithelial cells trigger cytolysis, localized tissue necrosis, and marked oral pain, which often leads to poor oral intake and dehydration

Pathophysiologically, local viral invasion and replication within mucosal epithelial cells trigger cytolysis, localized tissue necrosis, and marked oral pain, which often leads to poor oral intake and dehydration