Gout

Gout is a common, chronic metabolic disorder and form of inflammatory arthritis characterized by the precipitation and deposition of monosodium urate monohydrate crystals in synovial joints and periarticular soft tissues Clinically, gout most often affects middle-aged and older adults, particularly men and postmenopausal women, typically presenting as acute, exquisitely painful, and self-limited monoarticular flares that predominantly involve the first metatarsophalangeal joint or other lower-ex...

Gout is a common, chronic metabolic disorder and form of inflammatory arthritis characterized by the precipitation and deposition of monosodium urate monohydrate crystals in synovial joints and periarticular soft tissues

It is driven by persistent hyperuricemia resulting from urate overproduction, impaired renal or gastrointestinal excretion, or both Left unmanaged, repeated inflammatory episodes can progress to chronic gouty arthropathy, joint destruction, nephrolithiasis, and the subcutaneous accumulation of nodular crystal aggregates known as tophi

Clinically, gout most often affects middle-aged and older adults, particularly men and postmenopausal women, typically presenting as acute, exquisitely painful, and self-limited monoarticular flares that predominantly involve the first metatarsophalangeal joint or other lower-extremity joints

Left unmanaged, repeated inflammatory episodes can progress to chronic gouty arthropathy, joint destruction, nephrolithiasis, and the subcutaneous accumulation of nodular crystal aggregates known as tophi

Left unmanaged, repeated inflammatory episodes can progress to chronic gouty arthropathy, joint destruction, nephrolithiasis, and the subcutaneous accumulation of nodular crystal aggregates known as tophi