Indication

Humoral hypercalcemia of malignancy

Humoral hypercalcemia of malignancy is a systemic metabolic paraneoplastic syndrome that occurs in patients with advanced cancers, most commonly squamous cell carcinomas, renal cell carcinoma, ovarian cancer, and breast carcinoma. Read more about Humoral hypercalcemia of malignancy

385 drugs 179 manufacturers

Advertisement

Drugs that treat it

Common Humoral hypercalcemia of malignancy therapies.

Showing 226–234 of 385 drugs

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
QUALITY CARE

PREDNISONE

GLUCOCORTICOSTEROIDS·PULMONARY TUBERCULOSIS·+67
UNIT DOSE SERVI

ZOLEDRONIC ACID

HYPERCALCEMIA AGENTS·HUMORAL HYPERCALCEMIA OF MALIGNANCY·+2
INGENUS PHARMAC

DEXAMETHASONE

GLUCOCORTICOSTEROIDS·DISSEMINATED TUBERCULOSIS·+61
A-S MEDICATION
Filter & compare in the drug finder →Opens the drug finder with Humoral hypercalcemia of malignancy preselected.

News & literature

Coming soon

Related codes

Coming soon
Coming soon

About Humoral hypercalcemia of malignancy.

Humoral hypercalcemia of malignancy is a systemic metabolic paraneoplastic syndrome that occurs in patients with advanced cancers, most commonly squamous cell carcinomas, renal cell carcinoma, ovarian cancer, and breast carcinoma.

It affects the skeletal and renal systems through the tumor-driven secretion of circulating factors, overwhelmingly parathyroid hormone-related protein (PTHrP), without requiring direct skeletal metastases.

Clinically and pathophysiologically, circulating PTHrP binds to parathyroid hormone receptors, triggering profound osteoclastic bone resorption and stimulating renal tubular calcium reabsorption while promoting phosphate wasting, which leads to severe, often life-threatening elevations in serum calcium.

Personalize your experience

Follow Humoral hypercalcemia of malignancy and get updates as they land.

Create a free account

Follow an indication and get alerts when its drugs, labels, or guidelines change

Save any drug on this page to your favorites, synced across devices

AI-curated peer-reviewed research, summarized for your specialty

A morning digest of indication-relevant updates, when you want it