Indication
Hypercalcemia due to primary hyperparathyroidism
Hypercalcemia due to primary hyperparathyroidism is an endocrine condition marked by elevated serum calcium concentrations resulting from the autonomous, unregulated overproduction of parathyroid hormone (PTH) by one or more abnormal parathyroid glands, most frequently a benign solitary adenoma. Read more about Hypercalcemia due to primary hyperparathyroidism
19 drugs 16 manufacturers
Drugs that treat it
Common Hypercalcemia due to primary hyperparathyroidism therapies.
CINACALCET HCL
CINACALCET HCL
CINACALCET (cinacalcet HCl)
CINACALCET (cinacalcet HCl)
CINACALCET (cinacalcet HCl)
CINACALCET (cinacalcet HCl)
CINACALCET HCL
CINACALCET HCL
News & literature
Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonHypercalcemia due to primary hyperparathyroidism is an endocrine condition marked by elevated serum calcium concentrations resulting from the autonomous, unregulated overproduction of parathyroid hormone (PTH) by one or more abnormal parathyroid glands, most frequently a benign solitary adenoma.
It primarily affects adults—most commonly postmenopausal women—and involves disrupted calcium homeostasis across the skeletal, renal, and gastrointestinal systems.
Pathophysiologically, inappropriate excess PTH stimulates osteoclastic bone resorption, increases renal tubular reabsorption of calcium, and enhances 1,25-dihydroxyvitamin D synthesis to promote intestinal calcium absorption.
Clinically, it ranges from asymptomatic hypercalcemia detected on routine blood testing to overt disease manifesting with nephrolithiasis, decreased bone mineral density, osteopenia, bone fractures, and neuromuscular or neuropsychiatric symptoms.
- nih.gov
Hypercalcemia due to primary hyperparathyroidism is an endocrine condition marked by elevated serum calcium concentrations resulting from the autonomous, unregulated overproduction of parathyroid hormone (PTH) by one or more abnormal parathyroid glands, most frequently a benign solitary adenoma It primarily affects adults—most commonly postmenopausal women—and involves disrupted calcium homeostasis across the skeletal, renal, and gastrointestinal systems Pathophysiologically, inappropriate exces...
- nih.gov
Clinically, it ranges from asymptomatic hypercalcemia detected on routine blood testing to overt disease manifesting with nephrolithiasis, decreased bone mineral density, osteopenia, bone fractures, and neuromuscular or neuropsychiatric symptoms
- nih.gov
Clinically, it ranges from asymptomatic hypercalcemia detected on routine blood testing to overt disease manifesting with nephrolithiasis, decreased bone mineral density, osteopenia, bone fractures, and neuromuscular or neuropsychiatric symptoms
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