Indication
Hyperkeratosis
Hyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes. Read more about Hyperkeratosis
117 drugs 45 manufacturers
Drugs that treat it
Common Hyperkeratosis therapies.
TRANS-VER-SAL PEDIAPATCH (salicylic acid)
SALACTIC FILM (salicylic acid/collodion, flexible)
GORDOFILM (salicylic acid/lactic acid/collodion, flexible)
CALLUS REMOVER (salicylic acid)
SALEX (salicylic acid)
SALEX (salicylic acid/ceramides 1,3,6-II)
SALEX (salicylic acid/ceramides 1,3,6-II)
EXFOLIATING MOISTURIZER (salicylic acid/urea/petrolatum,white)
News & literature
Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonHyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes.
It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules.
Pathophysiologically, it arises as a protective physiologic response to chronic friction, or secondary to underlying inflammatory dermatoses, genetic disorders of cornification, or premalignant alterations.
Histologically, it is broadly subclassified into orthokeratotic hyperkeratosis, where keratinocyte maturation is preserved without retained nuclei, and parakeratotic hyperkeratosis, marked by retained cellular nuclei reflecting altered epidermal transit.
- nih.gov
Hyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules Pathophysiologically, it arises as a protective physiologic response to chronic friction, or secondary to underlying inflammato...
- nih.gov
Hyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes
- clevelandclinic.org
It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules
- harvard.edu
It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules
- medicalnewstoday.com
Pathophysiologically, it arises as a protective physiologic response to chronic friction, or secondary to underlying inflammatory dermatoses, genetic disorders of cornification, or premalignant alterations
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