Hypocalcemia

Hypocalcemia is an electrolyte disorder characterized by abnormally low concentrations of total serum calcium or physiologically active ionized calcium It primarily affects the neuromuscular and cardiovascular systems, frequently arising from hypoparathyroidism, vitamin D deficiency, chronic kidney disease, hypomagnesemia, or acute critical illness

Hypocalcemia is an electrolyte disorder characterized by abnormally low concentrations of total serum calcium or physiologically active ionized calcium Pathophysiologically, reduced extracellular calcium lowers the threshold potential of excitable cells, leading to heightened neuromuscular irritability that manifests as perioral paresthesias, muscle cramping, carpopedal spasms, and positive Chvostek or Trousseau signs Severe or rapid declines can produce life-threatening complications, including...

It primarily affects the neuromuscular and cardiovascular systems, frequently arising from hypoparathyroidism, vitamin D deficiency, chronic kidney disease, hypomagnesemia, or acute critical illness

Pathophysiologically, reduced extracellular calcium lowers the threshold potential of excitable cells, leading to heightened neuromuscular irritability that manifests as perioral paresthesias, muscle cramping, carpopedal spasms, and positive Chvostek or Trousseau signs

Severe or rapid declines can produce life-threatening complications, including tetany, laryngospasm, seizures, prolonged electrocardiographic QT intervals, and cardiac arrhythmias