ZERBAXA (ceftolozane sulfate/tazobactam sodium)
BETA-LACTAMS·NOSOCOMIAL BACTERIAL PNEUMONIA·+25
Merck Sharp & Dohme
Indication
Klebsiella complicated UTI
A *Klebsiella* complicated urinary tract infection is an infection of the urinary tract—including the bladder, ureters, or kidneys—caused by Gram-negative bacilli of the genus *Klebsiella* (predominantly *Klebsiella pneumoniae*). Read more about Klebsiella complicated UTI
119 drugs 64 manufacturers
Drugs that treat it
Common Klebsiella complicated UTI therapies.
ZEMDRI (plazomicin sulfate)
AMINOGLYCOSIDES, PARENTERAL·COMPLICATED PROTEUS UTI·+3
CIPLA THERAPEUT
ERTAPENEM (ertapenem sodium)
BETA-LACTAMS·PNEUMOCOCCAL PNEUMONIA·+42
NORTHSTAR RX LL
TOBRAMYCIN SULFATE
AMINOGLYCOSIDES, PARENTERAL·E. COLI SEPTICEMIA·+44
NORTHSTAR RX LL
ERTAPENEM (ertapenem sodium)
BETA-LACTAMS·PNEUMOCOCCAL PNEUMONIA·+42
WG CRITICAL CAR
ERTAPENEM (ertapenem sodium)
BETA-LACTAMS·PNEUMOCOCCAL PNEUMONIA·+42
DR.REDDY'S LAB
TOBRAMYCIN SULFATE
AMINOGLYCOSIDES, PARENTERAL·E. COLI SEPTICEMIA·+44
SLATE RUN PHARM
CEFEPIME HCL
BETA-LACTAMS·FEBRILE NEUTROPENIC PATIENT PRESUMED INFECTION TREATMENT·+26
XELLIA PHARMACE
ERTAPENEM (ertapenem sodium)
BETA-LACTAMS·PNEUMOCOCCAL PNEUMONIA·+42
FOSUN PHARMA US
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News & literature
Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonA *Klebsiella* complicated urinary tract infection is an infection of the urinary tract—including the bladder, ureters, or kidneys—caused by Gram-negative bacilli of the genus *Klebsiella* (predominantly *Klebsiella pneumoniae*).
It develops in individuals with factors that compromise urinary tract defenses or increase treatment failure risk, such as structural abnormalities, urinary obstruction, neurogenic dysfunction, indwelling urinary catheters, immunosuppression, or advanced age.
Pathophysiologically, *Klebsiella* relies on virulence traits including a protective polysaccharide capsule, adhesins, and robust biofilm formation that facilitate adherence and persistence on uroepithelial cells and catheter surfaces.
Clinically, it frequently manifests as pyelonephritis or severe lower tract disease, carries an elevated risk of multidrug resistance through extended-spectrum beta-lactamases or carbapenemases, and can rapidly progress to bacteremia and urosepsis.
- nih.gov
A *Klebsiella* complicated urinary tract infection is an infection of the urinary tract—including the bladder, ureters, or kidneys—caused by Gram-negative bacilli of the genus *Klebsiella* (predominantly *Klebsiella pneumoniae*) It develops in individuals with factors that compromise urinary tract defenses or increase treatment failure risk, such as structural abnormalities, urinary obstruction, neurogenic dysfunction, indwelling urinary catheters, immunosuppression, or advanced age
- fda.gov
A *Klebsiella* complicated urinary tract infection is an infection of the urinary tract—including the bladder, ureters, or kidneys—caused by Gram-negative bacilli of the genus *Klebsiella* (predominantly *Klebsiella pneumoniae*) Clinically, it frequently manifests as pyelonephritis or severe lower tract disease, carries an elevated risk of multidrug resistance through extended-spectrum beta-lactamases or carbapenemases, and can rapidly progress to bacteremia and urosepsis
- umn.edu
A *Klebsiella* complicated urinary tract infection is an infection of the urinary tract—including the bladder, ureters, or kidneys—caused by Gram-negative bacilli of the genus *Klebsiella* (predominantly *Klebsiella pneumoniae*)
- nih.gov
Pathophysiologically, *Klebsiella* relies on virulence traits including a protective polysaccharide capsule, adhesins, and robust biofilm formation that facilitate adherence and persistence on uroepithelial cells and catheter surfaces
- nih.gov
Clinically, it frequently manifests as pyelonephritis or severe lower tract disease, carries an elevated risk of multidrug resistance through extended-spectrum beta-lactamases or carbapenemases, and can rapidly progress to bacteremia and urosepsis
- nih.gov
Clinically, it frequently manifests as pyelonephritis or severe lower tract disease, carries an elevated risk of multidrug resistance through extended-spectrum beta-lactamases or carbapenemases, and can rapidly progress to bacteremia and urosepsis
- idsociety.org
Clinically, it frequently manifests as pyelonephritis or severe lower tract disease, carries an elevated risk of multidrug resistance through extended-spectrum beta-lactamases or carbapenemases, and can rapidly progress to bacteremia and urosepsis
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