Indication

Klebsiella pneumoniae osteomyelitis

*Klebsiella pneumoniae* osteomyelitis is an uncommon and serious bacterial infection of the skeletal system involving cortical bone and bone marrow, caused by the Gram-negative bacillus *Klebsiella pneumoniae*. Read more about Klebsiella pneumoniae osteomyelitis

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About Klebsiella pneumoniae osteomyelitis.

*Klebsiella pneumoniae* osteomyelitis is an uncommon and serious bacterial infection of the skeletal system involving cortical bone and bone marrow, caused by the Gram-negative bacillus *Klebsiella pneumoniae*.

The disease most often arises via hematogenous dissemination from primary respiratory, urinary, or abdominal foci, or through direct contamination from trauma, surgery, or contiguous soft-tissue ulcers.

It disproportionately impacts vulnerable populations, including individuals with diabetes mellitus, chronic liver disease, or immunocompromising conditions, as well as hospitalized patients with indwelling devices.

Pathophysiologically, the condition is characterized by progressive osseous inflammation, vascular occlusion leading to bone necrosis and sequestrum formation, localized periosteal reaction, and clinical manifestations such as localized bone pain, swelling, erythema, and fever.

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