Legionnaires' disease

Legionnaires' disease is a severe, potentially life-threatening form of pneumonia caused by aerobic, gram-negative bacilli of the genus *Legionella*, most commonly *Legionella pneumophila* Pathophysiologically, the bacteria replicate intracellularly within alveolar macrophages, inciting an intense inflammatory response within the lower respiratory tract

Legionnaires' disease is a severe, potentially life-threatening form of pneumonia caused by aerobic, gram-negative bacilli of the genus *Legionella*, most commonly *Legionella pneumophila* Transmission occurs via inhalation or aspiration of aerosolized, contaminated water from human-made water systems, disproportionately impacting older adults, smokers, and immunocompromised individuals

Legionnaires' disease is a severe, potentially life-threatening form of pneumonia caused by aerobic, gram-negative bacilli of the genus *Legionella*, most commonly *Legionella pneumophila* Pathophysiologically, the bacteria replicate intracellularly within alveolar macrophages, inciting an intense inflammatory response within the lower respiratory tract Clinically, it presents with high fever, cough, dyspnea, and pulmonary consolidation, often accompanied by prominent extrapulmonary manifestatio...

Transmission occurs via inhalation or aspiration of aerosolized, contaminated water from human-made water systems, disproportionately impacting older adults, smokers, and immunocompromised individuals Clinically, it presents with high fever, cough, dyspnea, and pulmonary consolidation, often accompanied by prominent extrapulmonary manifestations such as gastrointestinal disturbances, neurologic alterations, and hyponatremia

Clinically, it presents with high fever, cough, dyspnea, and pulmonary consolidation, often accompanied by prominent extrapulmonary manifestations such as gastrointestinal disturbances, neurologic alterations, and hyponatremia