Lennox-Gastaut epilepsy

Lennox-Gastaut epilepsy, commonly referred to as Lennox-Gastaut syndrome (LGS), is a severe, lifelong developmental and epileptic encephalopathy that typically manifests in early childhood between the ages of two and eight years

Lennox-Gastaut epilepsy, commonly referred to as Lennox-Gastaut syndrome (LGS), is a severe, lifelong developmental and epileptic encephalopathy that typically manifests in early childhood between the ages of two and eight years Primarily affecting the central nervous system, it is clinically characterized by a triad of multiple drug-resistant seizure types—most notably tonic, atonic, and atypical absence seizures—alongside moderate to severe cognitive impairment and behavioral disturbances

Lennox-Gastaut epilepsy, commonly referred to as Lennox-Gastaut syndrome (LGS), is a severe, lifelong developmental and epileptic encephalopathy that typically manifests in early childhood between the ages of two and eight years

Primarily affecting the central nervous system, it is clinically characterized by a triad of multiple drug-resistant seizure types—most notably tonic, atonic, and atypical absence seizures—alongside moderate to severe cognitive impairment and behavioral disturbances The defining pathophysiologic neurodiagnostic features include generalized interictal slow spike-and-wave discharges of less than 3 Hz during wakefulness and generalized paroxysmal fast activity during sleep Frequent tonic and atonic...

Primarily affecting the central nervous system, it is clinically characterized by a triad of multiple drug-resistant seizure types—most notably tonic, atonic, and atypical absence seizures—alongside moderate to severe cognitive impairment and behavioral disturbances

The defining pathophysiologic neurodiagnostic features include generalized interictal slow spike-and-wave discharges of less than 3 Hz during wakefulness and generalized paroxysmal fast activity during sleep Frequent tonic and atonic episodes frequently trigger precipitous drop attacks, presenting a high risk for recurrent injury and status epilepticus

The defining pathophysiologic neurodiagnostic features include generalized interictal slow spike-and-wave discharges of less than 3 Hz during wakefulness and generalized paroxysmal fast activity during sleep

Frequent tonic and atonic episodes frequently trigger precipitous drop attacks, presenting a high risk for recurrent injury and status epilepticus