Listeriosis

Listeriosis is a bacterial infection primarily caused by the ingestion of food contaminated with the gram-positive, facultative intracellular rod *Listeria monocytogenes*

Listeriosis is a bacterial infection primarily caused by the ingestion of food contaminated with the gram-positive, facultative intracellular rod *Listeria monocytogenes*

While immunocompetent hosts typically experience self-limiting febrile gastroenteritis, severe invasive disease predominantly develops in vulnerable populations, including pregnant women, neonates, elderly adults, and immunocompromised individuals Pathophysiologically, the organism crosses the intestinal barrier, disseminates hematogenously, and evades cell-mediated immunity to traverse endothelial and blood-brain barriers, most commonly resulting in bacteremia, meningitis, or meningoencephaliti...

While immunocompetent hosts typically experience self-limiting febrile gastroenteritis, severe invasive disease predominantly develops in vulnerable populations, including pregnant women, neonates, elderly adults, and immunocompromised individuals

Pathophysiologically, the organism crosses the intestinal barrier, disseminates hematogenously, and evades cell-mediated immunity to traverse endothelial and blood-brain barriers, most commonly resulting in bacteremia, meningitis, or meningoencephalitis

In maternal-neonatal infections, transplacental transmission or peripartum exposure frequently leads to miscarriage, stillbirth, premature labor, or fulminant neonatal sepsis