Indication

Lyme disease

Lyme disease is a multisystem tick-borne zoonosis primarily caused by spirochetes of the *Borrelia burgdorferi* sensu lato complex, transmitted through the bite of infected *Ixodes* species ticks. Read more about Lyme disease

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About Lyme disease.

Lyme disease is a multisystem tick-borne zoonosis primarily caused by spirochetes of the *Borrelia burgdorferi* sensu lato complex, transmitted through the bite of infected *Ixodes* species ticks.

It affects pediatric and adult populations exposed to endemic wooded or grassy habitats, progressing across early localized, early disseminated, and late stages.

Clinically, early infection frequently presents with an expanding erythema migrans skin lesion accompanied by nonspecific constitutional symptoms such as fever, fatigue, and arthralgia.

If untreated, hematogenous dissemination can involve the nervous system, myocardium, and joints, producing cranial nerve palsies, carditis with conduction blocks, or recurrent oligoarticular arthritis, most notably in the knees.

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