Lymphogranuloma venereum

Lymphogranuloma venereum is a systemic sexually transmitted infection caused by invasive L1, L2, or L3 serovars of the bacterium *Chlamydia trachomatis* The pathogen preferentially targets regional lymphatic tissues and mucosal surfaces, classically producing a transient, painless primary genital ulcer followed by painful inguinal or femoral lymphadenopathy with suppurative bubo formation Particularly among men who have sex with men, it frequently manifests as severe, invasive proctocolitis mark...

Lymphogranuloma venereum is a systemic sexually transmitted infection caused by invasive L1, L2, or L3 serovars of the bacterium *Chlamydia trachomatis* The pathogen preferentially targets regional lymphatic tissues and mucosal surfaces, classically producing a transient, painless primary genital ulcer followed by painful inguinal or femoral lymphadenopathy with suppurative bubo formation

The pathogen preferentially targets regional lymphatic tissues and mucosal surfaces, classically producing a transient, painless primary genital ulcer followed by painful inguinal or femoral lymphadenopathy with suppurative bubo formation If left untreated, chronic lymphatic obstruction and persistent inflammation can result in irreversible complications, including genital elephantiasis, fistulas, and colorectal strictures