Major nerve block for surgery

"Major nerve block for surgery" is an anesthetic procedure rather than a disease or clinical pathology, designated as a therapeutic indication for local anesthetics to establish regional surgical anesthesia and perioperative analgesia

"Major nerve block for surgery" is an anesthetic procedure rather than a disease or clinical pathology, designated as a therapeutic indication for local anesthetics to establish regional surgical anesthesia and perioperative analgesia

This technique involves targeted perineural infiltration around extensive peripheral neural structures—such as nerve plexuses (e.g., brachial or lumbar plexus) or large discrete nerve trunks (e.g., sciatic or femoral nerves)—supplying distinct anatomical regions, primarily within the musculoskeletal and peripheral nervous systems It temporarily arrests action potential propagation along sensory, autonomic, and motor fibers via voltage-gated sodium channel inhibition, resulting in profound region...

This technique involves targeted perineural infiltration around extensive peripheral neural structures—such as nerve plexuses (e.g., brachial or lumbar plexus) or large discrete nerve trunks (e.g., sciatic or femoral nerves)—supplying distinct anatomical regions, primarily within the musculoskeletal and peripheral nervous systems

It temporarily arrests action potential propagation along sensory, autonomic, and motor fibers via voltage-gated sodium channel inhibition, resulting in profound regional loss of sensation, muscle relaxation, and ablation of surgical pain signaling without the obligate depression of the central nervous system associated with general anesthesia