Metabolic acidosis

Metabolic acidosis is a systemic acid-base disorder characterized by a primary reduction in serum bicarbonate concentration, typically accompanied by a decrease in arterial blood pH and a compensatory decrease in arterial partial pressure of carbon dioxide Clinically categorized into high anion gap or normal anion gap (hyperchloremic) subtypes, the disturbance frequently manifests with compensatory hyperventilation (Kussmaul breathing), altered mental status, and, if severe or uncorrected, hemod...

Metabolic acidosis is a systemic acid-base disorder characterized by a primary reduction in serum bicarbonate concentration, typically accompanied by a decrease in arterial blood pH and a compensatory decrease in arterial partial pressure of carbon dioxide

It arises when endogenous nonvolatile acid production increases (such as in ketoacidosis or lactic acidosis), acid excretion by the kidneys is impaired (as seen in acute kidney injury or chronic kidney disease), exogenous acidic toxins are ingested, or excessive bicarbonate is lost via the gastrointestinal tract or renal tubules

It arises when endogenous nonvolatile acid production increases (such as in ketoacidosis or lactic acidosis), acid excretion by the kidneys is impaired (as seen in acute kidney injury or chronic kidney disease), exogenous acidic toxins are ingested, or excessive bicarbonate is lost via the gastrointestinal tract or renal tubules

It arises when endogenous nonvolatile acid production increases (such as in ketoacidosis or lactic acidosis), acid excretion by the kidneys is impaired (as seen in acute kidney injury or chronic kidney disease), exogenous acidic toxins are ingested, or excessive bicarbonate is lost via the gastrointestinal tract or renal tubules

Clinically categorized into high anion gap or normal anion gap (hyperchloremic) subtypes, the disturbance frequently manifests with compensatory hyperventilation (Kussmaul breathing), altered mental status, and, if severe or uncorrected, hemodynamic instability and impaired cellular function

Clinically categorized into high anion gap or normal anion gap (hyperchloremic) subtypes, the disturbance frequently manifests with compensatory hyperventilation (Kussmaul breathing), altered mental status, and, if severe or uncorrected, hemodynamic instability and impaired cellular function

Clinically categorized into high anion gap or normal anion gap (hyperchloremic) subtypes, the disturbance frequently manifests with compensatory hyperventilation (Kussmaul breathing), altered mental status, and, if severe or uncorrected, hemodynamic instability and impaired cellular function