Indication

Muscle spasticity due to multiple sclerosis

Muscle spasticity due to multiple sclerosis is a chronic neuromuscular manifestation of the upper motor neuron syndrome resulting from autoimmune demyelination and axonal degeneration within the central nervous system. Read more about Muscle spasticity due to multiple sclerosis

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Drugs that treat it

Common Muscle spasticity due to multiple sclerosis therapies.

Showing 1–9 of 15 drugs

OZOBAX (baclofen)

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
METACEL PHARMAC

FLEQSUVY (baclofen)

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
SILVERGATE PHAR

BACLOFEN

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
WILSHIRE PHARMA

BACLOFEN

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
ANI PHARMACEUTI

BACLOFEN

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
PALMETTO PHARMA

BACLOFEN

CENTRAL MUSCLE RELAXANTS·MUSCLE SPASTICITY OF SPINAL ORIGIN·+1
SARRAS HEALTH,
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About Muscle spasticity due to multiple sclerosis.

Muscle spasticity due to multiple sclerosis is a chronic neuromuscular manifestation of the upper motor neuron syndrome resulting from autoimmune demyelination and axonal degeneration within the central nervous system.

It predominantly affects adults with multiple sclerosis, frequently involving the lower extremities and axial musculature.

Pathophysiologically, inflammatory demyelinating lesions disrupt descending corticospinal and reticulospinal pathways, impairing supraspinal inhibitory control and producing muscle spindle hyperexcitability.

Clinically, it is characterized by a velocity-dependent increase in tonic stretch reflexes, sustained muscle stiffness, involuntary and often painful spasms, clonus, and progressive mobility impairment.

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