Neuropathic pain associated with spinal cord injury

Neuropathic pain associated with spinal cord injury is a chronic central neuropathic pain condition resulting directly from traumatic or non-traumatic damage to the spinal cord

Neuropathic pain associated with spinal cord injury is a chronic central neuropathic pain condition resulting directly from traumatic or non-traumatic damage to the spinal cord Affecting individuals living with spinal cord injuries, the condition manifests as severe dysesthesia and persistent or paroxysmal pain, typically described as burning, stabbing, shooting, or electric shock–like sensations localized at or below the anatomical level of the lesion It is pathologically driven by central sens...

Affecting individuals living with spinal cord injuries, the condition manifests as severe dysesthesia and persistent or paroxysmal pain, typically described as burning, stabbing, shooting, or electric shock–like sensations localized at or below the anatomical level of the lesion It is pathologically driven by central sensitization, disruption of ascending spinothalamic pathways, loss of descending inhibitory controls, and hyperexcitability of deafferented dorsal horn neurons, frequently co-occur...

It is pathologically driven by central sensitization, disruption of ascending spinothalamic pathways, loss of descending inhibitory controls, and hyperexcitability of deafferented dorsal horn neurons, frequently co-occurring with hyperalgesia and allodynia