Non-Hodgkin's lymphoma

Non-Hodgkin's lymphoma is a diverse group of hematologic malignancies originating from lymphoid tissues, primarily affecting B lymphocytes and less commonly T lymphocytes or natural killer (NK) cells This disease directly involves the lymphatic and immune systems, frequently manifesting as painless lymphadenopathy in the neck, axillae, or groin, with potential dissemination to the spleen, bone marrow, and extranodal organs Clinically, it ranges from indolent to aggressive forms and often present...

Non-Hodgkin's lymphoma is a diverse group of hematologic malignancies originating from lymphoid tissues, primarily affecting B lymphocytes and less commonly T lymphocytes or natural killer (NK) cells Pathophysiologically, it is driven by genetic mutations that cause the uncontrolled clonal proliferation, survival, and accumulation of abnormal lymphocytes without the presence of diagnostic Reed-Sternberg cells Clinically, it ranges from indolent to aggressive forms and often presents with systemi...

This disease directly involves the lymphatic and immune systems, frequently manifesting as painless lymphadenopathy in the neck, axillae, or groin, with potential dissemination to the spleen, bone marrow, and extranodal organs

This disease directly involves the lymphatic and immune systems, frequently manifesting as painless lymphadenopathy in the neck, axillae, or groin, with potential dissemination to the spleen, bone marrow, and extranodal organs

Pathophysiologically, it is driven by genetic mutations that cause the uncontrolled clonal proliferation, survival, and accumulation of abnormal lymphocytes without the presence of diagnostic Reed-Sternberg cells Clinically, it ranges from indolent to aggressive forms and often presents with systemic "B symptoms," including persistent fever, drenching night sweats, and unintentional weight loss

Pathophysiologically, it is driven by genetic mutations that cause the uncontrolled clonal proliferation, survival, and accumulation of abnormal lymphocytes without the presence of diagnostic Reed-Sternberg cells