Nongonococcal urethritis

Nongonococcal urethritis is an infectious inflammation of the urethra occurring primarily in sexually active men and characterized by the absence of *Neisseria gonorrhoeae* infection It is most frequently caused by pathogens such as *Chlamydia trachomatis* and *Mycoplasma genitalium*, although other organisms—including *Ureaplasma urealyticum*, *Trichomonas vaginalis*, and herpes simplex virus—or noninfectious irritants can also be responsible Clinically, it manifests with dysuria, urethral prur...

Nongonococcal urethritis is an infectious inflammation of the urethra occurring primarily in sexually active men and characterized by the absence of *Neisseria gonorrhoeae* infection

It is most frequently caused by pathogens such as *Chlamydia trachomatis* and *Mycoplasma genitalium*, although other organisms—including *Ureaplasma urealyticum*, *Trichomonas vaginalis*, and herpes simplex virus—or noninfectious irritants can also be responsible Pathophysiologically, it is defined by microscopic evidence of polymorphonuclear leukocytes in urethral secretions or first-void urine in the documented absence of gram-negative intracellular diplococci