Indication

Nosocomial pneumonia due to Serratia marcescens

Nosocomial pneumonia due to *Serratia marcescens* is a hospital-acquired lower respiratory tract infection caused by the opportunistic Gram-negative bacillus *Serratia marcescens*. Read more about Nosocomial pneumonia due to Serratia marcescens

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About Nosocomial pneumonia due to Serratia marcescens.

Nosocomial pneumonia due to *Serratia marcescens* is a hospital-acquired lower respiratory tract infection caused by the opportunistic Gram-negative bacillus *Serratia marcescens*.

It primarily affects hospitalized patients within intensive care settings, particularly individuals receiving invasive mechanical ventilation, those with prolonged inpatient stays, and immunocompromised hosts.

Pathophysiologically, the organism colonizes the respiratory epithelium often via contaminated medical devices, respiratory equipment, or healthcare personnel contact, triggering an acute inflammatory response in the pulmonary parenchyma.

Clinically, it presents with new or progressive pulmonary infiltrates, fever, leukocytosis, and purulent sputum, and it can progress to severe necrotizing bronchopneumonia, cavitation, or systemic sepsis, often complicated by intrinsic and inducible beta-lactamase-mediated antimicrobial resistance.

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