Parkinsonism

Parkinsonism is a clinical movement disorder syndrome characterized by motor dysfunction affecting the central nervous system, most commonly observed in middle-aged and older adults It is defined by the cardinal clinical features of bradykinesia accompanied by resting tremor, muscular rigidity, and postural instability While idiopathic Parkinson disease is the most frequent etiology, parkinsonism can also result from other neurodegenerative disorders, cerebrovascular lesions, central nervous sys...

Parkinsonism is a clinical movement disorder syndrome characterized by motor dysfunction affecting the central nervous system, most commonly observed in middle-aged and older adults It is defined by the cardinal clinical features of bradykinesia accompanied by resting tremor, muscular rigidity, and postural instability Pathophysiologically, the syndrome arises from disruptions in the basal ganglia and dopaminergic nigrostriatal motor pathways

Parkinsonism is a clinical movement disorder syndrome characterized by motor dysfunction affecting the central nervous system, most commonly observed in middle-aged and older adults While idiopathic Parkinson disease is the most frequent etiology, parkinsonism can also result from other neurodegenerative disorders, cerebrovascular lesions, central nervous system infections, toxins, or exposure to dopamine-receptor blocking medications

Pathophysiologically, the syndrome arises from disruptions in the basal ganglia and dopaminergic nigrostriatal motor pathways While idiopathic Parkinson disease is the most frequent etiology, parkinsonism can also result from other neurodegenerative disorders, cerebrovascular lesions, central nervous system infections, toxins, or exposure to dopamine-receptor blocking medications