Peripheral edema due to chronic heart failure

Peripheral edema due to chronic heart failure is a clinical manifestation of systemic fluid volume overload occurring in individuals with long-standing structural or functional cardiac impairment

Peripheral edema due to chronic heart failure is a clinical manifestation of systemic fluid volume overload occurring in individuals with long-standing structural or functional cardiac impairment Pathophysiologically, sustained impairment of ventricular ejection or filling triggers neurohormonal activation—most notably the renin-angiotensin-aldosterone and sympathetic nervous systems—causing secondary renal retention of sodium and water The resulting extracellular volume expansion and elevated c...

It primarily affects the cardiovascular, renal, and peripheral vascular systems, presenting as dependent, pitting soft-tissue swelling predominantly in the lower extremities, ankles, and feet The resulting extracellular volume expansion and elevated central venous and capillary hydrostatic pressures overcome plasma oncotic pressure and lymphatic drainage capacity, leading to pathological transudation of fluid into the interstitial space

It primarily affects the cardiovascular, renal, and peripheral vascular systems, presenting as dependent, pitting soft-tissue swelling predominantly in the lower extremities, ankles, and feet

It primarily affects the cardiovascular, renal, and peripheral vascular systems, presenting as dependent, pitting soft-tissue swelling predominantly in the lower extremities, ankles, and feet

Pathophysiologically, sustained impairment of ventricular ejection or filling triggers neurohormonal activation—most notably the renin-angiotensin-aldosterone and sympathetic nervous systems—causing secondary renal retention of sodium and water The resulting extracellular volume expansion and elevated central venous and capillary hydrostatic pressures overcome plasma oncotic pressure and lymphatic drainage capacity, leading to pathological transudation of fluid into the interstitial space