Indication

Plasmodium ovale malaria

**Plasmodium ovale malaria** is a mosquito-borne parasitic infection caused by the protozoan parasite *Plasmodium ovale* (encompassing the sympatric subspecies *P. Read more about Plasmodium ovale malaria

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About Plasmodium ovale malaria.

**Plasmodium ovale malaria** is a mosquito-borne parasitic infection caused by the protozoan parasite *Plasmodium ovale* (encompassing the sympatric subspecies *P.

ovale curtisi* and *P.

ovale wallikeri*).

Transmitted through the bites of infective female *Anopheles* mosquitoes, it predominantly affects residents of and travelers to endemic areas, most notably tropical West Africa and parts of the western Pacific.

The infection targets the hepatic and hematologic systems, characterized by the preferential invasion of reticulocytes and young erythrocytes, leading to typical tertian febrile paroxysms occurring every 48 hours, alongside chills, diaphoresis, headache, and fatigue.

A key pathophysiologic hallmark is the parasite's ability to form dormant intrahepatic stages known as hypnozoites, which can reactivate weeks to years after the primary infection to cause clinical relapse unless eradicated.

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