Postoperative acute pain

Postoperative acute pain is a complex, time-limited noxious sensory and emotional state arising directly from tissue trauma, incision, or visceral manipulation during a surgical intervention It affects surgical patients of all demographics across cutaneous, musculoskeletal, and visceral organ systems, mediated by primary afferent nociceptors and the peripheral and central nervous systems

Postoperative acute pain is a complex, time-limited noxious sensory and emotional state arising directly from tissue trauma, incision, or visceral manipulation during a surgical intervention

It affects surgical patients of all demographics across cutaneous, musculoskeletal, and visceral organ systems, mediated by primary afferent nociceptors and the peripheral and central nervous systems Pathophysiologically, it is characterized by local release of inflammatory mediators causing peripheral sensitization, alongside dorsal horn hyperexcitability resulting in central sensitization Clinically, it manifests as localized or radiating discomfort, primary hyperalgesia, allodynia, and moveme...

Clinically, it manifests as localized or radiating discomfort, primary hyperalgesia, allodynia, and movement-evoked pain that peaks in the immediate post-surgical period and diminishes as tissue healing progresses

Clinically, it manifests as localized or radiating discomfort, primary hyperalgesia, allodynia, and movement-evoked pain that peaks in the immediate post-surgical period and diminishes as tissue healing progresses