Prevention of vitamin D deficiency

Prevention of vitamin D deficiency is a prophylactic clinical strategy aimed at maintaining adequate circulating calcifediol (25-hydroxyvitamin D) levels to avert systemic disruption of calcium and phosphorus homeostasis Affecting the musculoskeletal and endocrine systems across neonates, children, and adults, the underlying state of deficiency typically arises from inadequate cutaneous synthesis under ultraviolet B irradiation, insufficient dietary or supplemental intake, or impaired intestinal...

Prevention of vitamin D deficiency is a prophylactic clinical strategy aimed at maintaining adequate circulating calcifediol (25-hydroxyvitamin D) levels to avert systemic disruption of calcium and phosphorus homeostasis Affecting the musculoskeletal and endocrine systems across neonates, children, and adults, the underlying state of deficiency typically arises from inadequate cutaneous synthesis under ultraviolet B irradiation, insufficient dietary or supplemental intake, or impaired intestinal...

Affecting the musculoskeletal and endocrine systems across neonates, children, and adults, the underlying state of deficiency typically arises from inadequate cutaneous synthesis under ultraviolet B irradiation, insufficient dietary or supplemental intake, or impaired intestinal absorption Pathophysiologically, depleted active vitamin D impairs intestinal calcium transport, triggering compensatory secondary hyperparathyroidism, increased bone resorption, and impaired mineralization

Without preventive intervention, sustained deficiency progresses to defective skeletal mineralization manifesting as rickets in pediatric populations, osteomalacia and osteoporosis in adults, and heightened fracture risk