Indication

Proteus joint infection

A Proteus joint infection is a bacterial septic arthritis or periprosthetic joint infection affecting native articular spaces or artificial joint hardware. Read more about Proteus joint infection

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About Proteus joint infection.

A Proteus joint infection is a bacterial septic arthritis or periprosthetic joint infection affecting native articular spaces or artificial joint hardware.

Primarily caused by *Proteus mirabilis* or *Proteus vulgaris*, this condition predominantly arises in older adults, immunocompromised individuals, or patients with underlying joint disease or indwelling urinary catheters following hematogenous seeding or perioperative contamination.

Pathophysiologically, bacterial proliferation within the synovial tissue or on implant surfaces triggers intense neutrophil infiltration, purulent synovial effusion, and cytokine release, frequently compounded by biofilm formation.

Clinically, it presents with acute or subacute articular pain, swelling, erythema, localized warmth, and restricted joint motility, carrying a high risk of rapid cartilage destruction and mechanical implant failure if untreated.

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