Indication

Proteus septicemia

Proteus septicemia is a severe, life-threatening bloodstream infection and dysregulated systemic inflammatory state caused by Gram-negative bacilli of the genus *Proteus*, most commonly *Proteus mirabilis* or *Proteus vulgaris*. Read more about Proteus septicemia

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About Proteus septicemia.

Proteus septicemia is a severe, life-threatening bloodstream infection and dysregulated systemic inflammatory state caused by Gram-negative bacilli of the genus *Proteus*, most commonly *Proteus mirabilis* or *Proteus vulgaris*.

It typically affects hospitalized, elderly, or immunocompromised individuals, frequently originating as a complication of obstructive nephrolithiasis, long-term indwelling urinary catheterization, or complex wound and intra-abdominal infections.

Pathophysiologically, bacterial dissemination into the vascular system triggers widespread immune activation, marked clinically by bacteremia, fever or hypothermia, tachycardia, tachypnea, and leukocytosis.

If untreated, the condition can rapidly progress to severe sepsis, hemodynamic collapse from septic shock, and multiple organ dysfunction.

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