Indication

Seasonal affective disorder

Seasonal affective disorder is a recurrent mood disorder characterized by major depressive episodes that follow a predictable seasonal pattern, typically presenting during late fall or winter and remitting in spring or summer. Read more about Seasonal affective disorder

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About Seasonal affective disorder.

Seasonal affective disorder is a recurrent mood disorder characterized by major depressive episodes that follow a predictable seasonal pattern, typically presenting during late fall or winter and remitting in spring or summer.

Primarily affecting the central nervous system, it is more commonly diagnosed in women and young adults, with increased prevalence at higher geographic latitudes.

Pathophysiologically, the condition is linked to diminished ambient sunlight disrupting circadian rhythms, melatonin production, and central serotonin neurotransmission.

Defining clinical features classically include pervasive depressed mood, lethargy, hypersomnia, carbohydrate craving, and weight gain, though a less frequent summer-onset variant can present with insomnia, decreased appetite, and psychomotor agitation.

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