Secondary syphilis

Secondary syphilis is the systemic, disseminated stage of syphilis, a sexually transmitted infection caused by the spirochete bacterium *Treponema pallidum* The condition predominantly affects the integumentary and reticuloendothelial systems, classically presenting with generalized lymphadenopathy and a diffuse, nonpruritic maculopapular rash that characteristically involves the palms and soles

Secondary syphilis is the systemic, disseminated stage of syphilis, a sexually transmitted infection caused by the spirochete bacterium *Treponema pallidum*

Secondary syphilis is the systemic, disseminated stage of syphilis, a sexually transmitted infection caused by the spirochete bacterium *Treponema pallidum* It typically arises weeks to months after the initial infection following the hematogenous and lymphatic spread of the organism throughout the body Other hallmark clinical features include condyloma lata in intertriginous areas, mucous patches, patchy alopecia, and constitutional symptoms such as fever, malaise, and myalgias

The condition predominantly affects the integumentary and reticuloendothelial systems, classically presenting with generalized lymphadenopathy and a diffuse, nonpruritic maculopapular rash that characteristically involves the palms and soles Other hallmark clinical features include condyloma lata in intertriginous areas, mucous patches, patchy alopecia, and constitutional symptoms such as fever, malaise, and myalgias

The condition predominantly affects the integumentary and reticuloendothelial systems, classically presenting with generalized lymphadenopathy and a diffuse, nonpruritic maculopapular rash that characteristically involves the palms and soles