Sepsis of newborn

Sepsis of the newborn, also termed neonatal sepsis, is a severe systemic bloodstream infection and dysregulated inflammatory response occurring in infants within the first 28 days of life It is categorized by timing of onset into early-onset sepsis—frequently acquired vertically via intrapartum exposure to maternal pathogens—and late-onset sepsis, predominantly caused by nosocomial or community-acquired organisms Pathophysiologically driven by immature neonatal immune defenses, the syndrome char...

Sepsis of the newborn, also termed neonatal sepsis, is a severe systemic bloodstream infection and dysregulated inflammatory response occurring in infants within the first 28 days of life

It is categorized by timing of onset into early-onset sepsis—frequently acquired vertically via intrapartum exposure to maternal pathogens—and late-onset sepsis, predominantly caused by nosocomial or community-acquired organisms

It is categorized by timing of onset into early-onset sepsis—frequently acquired vertically via intrapartum exposure to maternal pathogens—and late-onset sepsis, predominantly caused by nosocomial or community-acquired organisms Pathophysiologically driven by immature neonatal immune defenses, the syndrome characteristically manifests with subtle and non-specific signs, including temperature instability, respiratory distress, lethargy, poor feeding, apnea, and cardiovascular instability, which c...

Pathophysiologically driven by immature neonatal immune defenses, the syndrome characteristically manifests with subtle and non-specific signs, including temperature instability, respiratory distress, lethargy, poor feeding, apnea, and cardiovascular instability, which can rapidly progress to septic shock and multisystem organ failure