Indication

Serratia meningitis

*Serratia* meningitis is a rare, severe bacterial infection of the central nervous system characterized by inflammation of the meninges covering the brain and spinal cord. Read more about Serratia meningitis

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Drugs that treat it

Common Serratia meningitis therapies.

Showing 1–9 of 16 drugs

AMIKACIN SULFATE

AMINOGLYCOSIDES, PARENTERAL·STAPHYLOCOCCAL SEPTICEMIA·+60
SAGENT PHARMACE
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About Serratia meningitis.

*Serratia* meningitis is a rare, severe bacterial infection of the central nervous system characterized by inflammation of the meninges covering the brain and spinal cord.

Caused by opportunistic Gram-negative bacilli of the genus *Serratia* (predominantly *Serratia marcescens*), it primarily affects neonates in intensive care units, immunocompromised individuals, and neurosurgical patients following invasive instrumentation, craniotomy, or spinal procedures.

Pathophysiologically, the organism invades the subarachnoid space via hematogenous dissemination or direct inoculation, eliciting an intense inflammatory cascade marked by neutrophilic pleocytosis, elevated cerebrospinal fluid protein, and decreased glucose.

Clinically, affected patients present with hallmark features of meningeal irritation, including fever, headache, altered mental status, and nuchal rigidity, frequently complicated by hydrocephalus, brain abscess formation, or necrotizing ventriculitis.

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