Serratia osteomyelitis

Serratia osteomyelitis is an uncommon, invasive bacterial infection of the bone and bone marrow caused by species of the Gram-negative opportunistic bacillus *Serratia*, most frequently *Serratia marcescens* Pathophysiologically, the organism establishes inflammatory destruction within cortical bone and the medullary canal via hematogenous seeding—frequently targeting the axial skeleton, such as the vertebrae—or by contiguous spread from adjacent soft tissue

Serratia osteomyelitis is an uncommon, invasive bacterial infection of the bone and bone marrow caused by species of the Gram-negative opportunistic bacillus *Serratia*, most frequently *Serratia marcescens* The condition primarily affects immunocompromised individuals, patients with healthcare-associated exposures or indwelling instrumentation, people who inject drugs, and individuals who have sustained open trauma or surgical contamination

The condition primarily affects immunocompromised individuals, patients with healthcare-associated exposures or indwelling instrumentation, people who inject drugs, and individuals who have sustained open trauma or surgical contamination Pathophysiologically, the organism establishes inflammatory destruction within cortical bone and the medullary canal via hematogenous seeding—frequently targeting the axial skeleton, such as the vertebrae—or by contiguous spread from adjacent soft tissue Definin...

The condition primarily affects immunocompromised individuals, patients with healthcare-associated exposures or indwelling instrumentation, people who inject drugs, and individuals who have sustained open trauma or surgical contamination

Pathophysiologically, the organism establishes inflammatory destruction within cortical bone and the medullary canal via hematogenous seeding—frequently targeting the axial skeleton, such as the vertebrae—or by contiguous spread from adjacent soft tissue Defining clinical features include localized bone pain, erythema, swelling, tenderness, low-grade fevers, and radiographic evidence of osteolysis, periosteal reaction, or abscess formation

Defining clinical features include localized bone pain, erythema, swelling, tenderness, low-grade fevers, and radiographic evidence of osteolysis, periosteal reaction, or abscess formation