Severe burns

Severe burns are life-threatening injuries characterized by extensive thermal, chemical, electrical, or radiation destruction of the integumentary system, typically encompassing deep partial-thickness or full-thickness tissue damage and often involving substantial total body surface area

Severe burns are life-threatening injuries characterized by extensive thermal, chemical, electrical, or radiation destruction of the integumentary system, typically encompassing deep partial-thickness or full-thickness tissue damage and often involving substantial total body surface area While affecting individuals of all age groups, the condition frequently extends beyond local cutaneous necrosis to trigger profound systemic pathophysiology Defining features include widespread microvascular hyp...

While affecting individuals of all age groups, the condition frequently extends beyond local cutaneous necrosis to trigger profound systemic pathophysiology Defining features include widespread microvascular hyperpermeability leading to rapid plasma extravasation, hypovolemic burn shock, intense systemic inflammatory response syndrome, and a protracted hypermetabolic state accompanied by severe immunosuppression and multi-organ dysfunction