Tdap vaccination during third trimester pregnancy to prevent pertussis in infant

Pertussis, commonly known as whooping cough, is a highly contagious acute respiratory tract infection caused by the bacterium *Bordetella pertussis*

Pertussis, commonly known as whooping cough, is a highly contagious acute respiratory tract infection caused by the bacterium *Bordetella pertussis*

Neonates and infants under two months of age represent a particularly vulnerable population, as they are too young to receive primary active immunization and are at the greatest risk for severe disease, respiratory compromise, apnea, pneumonia, pulmonary hypertension, hospitalization, and death Administering the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during the third trimester of pregnancy induces high levels of maternal anti-pertussis antibodies that a...

Neonates and infants under two months of age represent a particularly vulnerable population, as they are too young to receive primary active immunization and are at the greatest risk for severe disease, respiratory compromise, apnea, pneumonia, pulmonary hypertension, hospitalization, and death Administering the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during the third trimester of pregnancy induces high levels of maternal anti-pertussis antibodies that a...

Neonates and infants under two months of age represent a particularly vulnerable population, as they are too young to receive primary active immunization and are at the greatest risk for severe disease, respiratory compromise, apnea, pneumonia, pulmonary hypertension, hospitalization, and death Administering the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during the third trimester of pregnancy induces high levels of maternal anti-pertussis antibodies that a...

Administering the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during the third trimester of pregnancy induces high levels of maternal anti-pertussis antibodies that are actively transferred across the placenta to the developing fetus, establishing passive immunity to protect the infant in the critical early months of life prior to routine childhood vaccination