Thyrotoxicosis crisis

A thyrotoxicosis crisis, also referred to as a thyrotoxic crisis or thyroid storm, is a rare, life-threatening endocrine emergency marked by an extreme and sudden exacerbation of thyrotoxicosis

A thyrotoxicosis crisis, also referred to as a thyrotoxic crisis or thyroid storm, is a rare, life-threatening endocrine emergency marked by an extreme and sudden exacerbation of thyrotoxicosis This hypermetabolic state predominantly affects the cardiovascular, central nervous, and gastrointestinal systems in individuals with preexisting, often untreated or poorly controlled, hyperthyroidism Pathophysiologically driven by an acute surge in thyroid hormone availability and an amplified responsive...

This hypermetabolic state predominantly affects the cardiovascular, central nervous, and gastrointestinal systems in individuals with preexisting, often untreated or poorly controlled, hyperthyroidism Pathophysiologically driven by an acute surge in thyroid hormone availability and an amplified responsiveness to catecholamines, it is typically triggered by precipitating stressors such as acute infection, trauma, surgery, or abrupt cessation of antithyroid medications Defining clinical features i...

Pathophysiologically driven by an acute surge in thyroid hormone availability and an amplified responsiveness to catecholamines, it is typically triggered by precipitating stressors such as acute infection, trauma, surgery, or abrupt cessation of antithyroid medications

Defining clinical features include severe hyperpyrexia, marked tachycardia or tachyarrhythmias, congestive heart failure, severe agitation, delirium, altered mental status, and a high risk of progression to multiorgan failure and cardiovascular collapse