Indication

Transurethral prostatectomy infection prevention

Transurethral prostatectomy infection prevention is a clinical indication for perioperative antimicrobial prophylaxis aimed at reducing the risk of postoperative infectious complications in adult male patients undergoing transurethral resection of the prostate (TURP). Read more about Transurethral prostatectomy infection prevention

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About Transurethral prostatectomy infection prevention.

Transurethral prostatectomy infection prevention is a clinical indication for perioperative antimicrobial prophylaxis aimed at reducing the risk of postoperative infectious complications in adult male patients undergoing transurethral resection of the prostate (TURP).

Because TURP is classified as a clean-contaminated urologic procedure involving the lower urinary tract, surgical instrumentation and tissue resection can disrupt mucosal barriers, aerosolize colonizing bacteria, or allow pathogens—predominantly uropathogenic Gram-negative bacilli such as *Escherichia coli* and common enterococci—to enter the bloodstream and open prostatic venous sinuses.

Prophylaxis targets the prevention of significant postoperative bacteriuria, symptomatic lower urinary tract infections, acute prostatitis, epididymitis, bacteremia, and urosepsis.

Clinical risk factors that heighten susceptibility in this setting include preoperative indwelling catheterization, urinary tract obstruction, and preexisting subclinical bacteriuria.

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