Tuberculosis meningitis

Tuberculosis meningitis (also referred to as tuberculous meningitis) is a severe, life-threatening extrapulmonary manifestation of central nervous system infection caused by *Mycobacterium tuberculosis* Patients generally present with a subacute progression of fever, headache, altered mental status, and meningismus, with cerebrospinal fluid analysis characteristically demonstrating lymphocytic pleocytosis, markedly elevated protein, and low glucose concentrations

Tuberculosis meningitis (also referred to as tuberculous meningitis) is a severe, life-threatening extrapulmonary manifestation of central nervous system infection caused by *Mycobacterium tuberculosis*

It typically arises following hematogenous dissemination from a primary focus, classically the lungs, and the subsequent rupture of subependymal or submeningeal granulomatous lesions (Rich foci) into the subarachnoid space

It typically arises following hematogenous dissemination from a primary focus, classically the lungs, and the subsequent rupture of subependymal or submeningeal granulomatous lesions (Rich foci) into the subarachnoid space Pathophysiologically, it is defined by dense, gelatinous inflammatory exudates that predominantly envelop the basal cisterns, which frequently causes cranial nerve neuropathies, obliterative vasculitis leading to cerebral infarction, and obstruction of cerebrospinal fluid flow...

Pathophysiologically, it is defined by dense, gelatinous inflammatory exudates that predominantly envelop the basal cisterns, which frequently causes cranial nerve neuropathies, obliterative vasculitis leading to cerebral infarction, and obstruction of cerebrospinal fluid flow resulting in hydrocephalus