Urticaria

Urticaria, commonly referred to as hives, is a vascular reaction pattern of the integumentary system that can affect individuals of any age Clinically, it is characterized by the sudden appearance of intensely pruritic, erythematous, edematous papules or plaques known as wheals, which may occur with or without concurrent angioedema Pathophysiologically, lesions arise when cutaneous mast cells and basophils degranulate, releasing histamine, platelet-activating factor, and other inflammatory media...

Urticaria, commonly referred to as hives, is a vascular reaction pattern of the integumentary system that can affect individuals of any age

Clinically, it is characterized by the sudden appearance of intensely pruritic, erythematous, edematous papules or plaques known as wheals, which may occur with or without concurrent angioedema

Pathophysiologically, lesions arise when cutaneous mast cells and basophils degranulate, releasing histamine, platelet-activating factor, and other inflammatory mediators

This mediator release induces transient localized vasodilation, increased capillary permeability, and sensory nerve stimulation in the superficial dermis, yielding circumscribed, migratory skin swelling that typically resolves within 24 hours without residual scarring