Vitamin D deficiency

Vitamin D deficiency is a metabolic nutritional disorder characterized by inadequate levels of circulating 25-hydroxyvitamin D, leading to impaired intestinal absorption of calcium and phosphorus This condition primarily affects the skeletal system across pediatric and adult populations, commonly driven by insufficient dietary intake, malabsorption, or limited ultraviolet B sun exposure Pathophysiologically, the resulting hypocalcemia stimulates secondary hyperparathyroidism, which mobilizes cal...

Vitamin D deficiency is a metabolic nutritional disorder characterized by inadequate levels of circulating 25-hydroxyvitamin D, leading to impaired intestinal absorption of calcium and phosphorus

This condition primarily affects the skeletal system across pediatric and adult populations, commonly driven by insufficient dietary intake, malabsorption, or limited ultraviolet B sun exposure Pathophysiologically, the resulting hypocalcemia stimulates secondary hyperparathyroidism, which mobilizes calcium from bone and leads to defective mineralization

Pathophysiologically, the resulting hypocalcemia stimulates secondary hyperparathyroidism, which mobilizes calcium from bone and leads to defective mineralization

Clinically, it manifests as rickets and impaired skeletal development in children, or osteomalacia, accelerated bone turnover, osteoporosis, and an increased risk of fragility fractures in adults