Zaire ebolavirus infection

*Zaire ebolavirus* infection is an acute, severe viral hemorrhagic disease caused by the *Zaire ebolavirus* (species *Orthoebolavirus zairense*), a single-stranded RNA virus in the family *Filoviridae*

*Zaire ebolavirus* infection is an acute, severe viral hemorrhagic disease caused by the *Zaire ebolavirus* (species *Orthoebolavirus zairense*), a single-stranded RNA virus in the family *Filoviridae* The infection affects both pediatric and adult populations, initiating with non-specific constitutional manifestations such as high fever, severe fatigue, headache, and myalgias, which rapidly progress to profuse gastrointestinal fluid loss, including intractable vomiting and diarrhea Without prom...

The infection affects both pediatric and adult populations, initiating with non-specific constitutional manifestations such as high fever, severe fatigue, headache, and myalgias, which rapidly progress to profuse gastrointestinal fluid loss, including intractable vomiting and diarrhea

The infection affects both pediatric and adult populations, initiating with non-specific constitutional manifestations such as high fever, severe fatigue, headache, and myalgias, which rapidly progress to profuse gastrointestinal fluid loss, including intractable vomiting and diarrhea

Pathophysiologically, the virus targets immune cells and vascular endothelium, precipitating extensive inflammatory cytokine release, microvascular leakage, and disseminated coagulopathy

Pathophysiologically, the virus targets immune cells and vascular endothelium, precipitating extensive inflammatory cytokine release, microvascular leakage, and disseminated coagulopathy

Without prompt intervention, this systemic dysregulation frequently leads to massive fluid shifts, hypovolemic shock, multiorgan failure, and high case fatality rates