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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,909–1,920 of 2,098 articles

PubMed

Performance Evaluation of Nucleic Acid Detection Reagents and Verification of Various Factors Affecting the Efficiency of Nucleic.

Background: Since the COVID-19 outbreak in 2019, nucleic acid testing has been central to epidemic control and clinical decision-making. However, variability in assay kits and extraction steps can affect sensitivity, specificity, and reproducibility. Systematic evaluation of detection reagents and extraction efficiency is essential to ensure reliable clinical results. Objective: This study aimed to evaluate whether three domestic novel coronavirus nucleic acid detection kits based on fluoresc...

Articles
Zhao D, Yuan J, Yuan F, Lin S, Yuan J•
PubMed

Enhanced H. pylori Treatment Using a β-Cyclodextrin-Propolis Complex: A Randomized Clinical Trial.

Background Helicobacter pylori infection poses a significant global health burden, with rising antibiotic resistance and treatment‐related side effects highlighting the need for adjunctive therapies. Propolis, a natural resin with known antimicrobial and anti‐inflammatory properties, suffers from poor solubility and bioavailability. This study evaluated a β‐cyclodextrin–propolis complex designed to enhance delivery and therapeutic efficacy in H. pylori‐infected patients. Materials and Methods...

Articles
Mehri A, Pourmoslemi S, Khalilian A, Safari M, Ayubi E•
PubMed

Anti-Helicobacter pylori Activity of Musa 'False Horn' (Musaceae), Syzygium aromaticum (Myrtaceae), Psidium guajava (Myrtaceae), Mangifera indica (Anacardiaceae), and Cymbopogon citratus (Poaceae) and Their Potential to Prevent and Eradicate H. pylori Biofilms.

Objectives The present study evaluated the antimicrobial activity of extracts from five Cameroonian medicinal plants against planktonic forms of Helicobacter pylori isolates and assessed their ability to inhibit biofilm formation and eradicate preformed biofilms. Methods The antimicrobial activity of 15 extracts obtained from Psidium guajava leaves, Mangifera indica leaves, Cymbopogon citratus aerial parts, Musa ‘False Horn’ ripe fruit peelings, and Syzygium aromaticum flower buds was evaluat...

Articles
Almeida KNC, Brigitte KML•
PubMed

Navigating Continuous Glucose Monitoring Adoption: Insights From Hispanic Adults With Insulin-Treated Type 2 Diabetes.

Objective Hispanic individuals are disproportionately affected by type 2 diabetes (T2D) and face access limitations in diabetes technology utilization. Despite proven benefits, continuous glucose monitoring (CGM) use remains low among Hispanic adults with insulin‐treated T2D. This study used a social–ecological model (SEM) framework to identify societal/policy, interpersonal/community, and individual level barriers to CGM access and adoption within this population. Methods Two focus groups we...

Articles
Soliman D, Arevalo G, Galindo RJ, Churba B, Malden KG, Jimenez DE, Pasquel FJ, Baidal DA, Walker AF•
PubMed

Postpartum Glycaemic Phenotype and Continuous Glucose Monitoring at 4-6 Years After Gestational Diabetes Defined by Different Diagnostic Criteria.

Aim To characterise glycaemic outcomes 4–6 years postpartum according to gestational diabetes mellitus (GDM) diagnostic thresholds and evaluate whether continuous glucose monitoring (CGM) identifies differences not captured by conventional clinical measures. Methods Women recruited before and after introduction of WHO GDM criteria were followed at 4 and 6 years postpartum. At each follow‐up, participants underwent oral glucose tolerance testing (OGTT), HbA1c measurement, body composition asse...

Articles
Andersson-Hall U, Kristiansson E, Åberg S, Törnqvist M, Wallenius K, Sengpiel V, Holmäng A•
PubMed

Characterizing Continuous Glucose Monitoring Prescription Patterns Between 2020 and 2024: A Retrospective Study at a Single Primary Care Facility in the United States.

Objective Examine the factors associated with continuous glucose monitoring (CGM) device prescriptions in a primary care facility. Materials and Methods We conducted a retrospective study of 1476 patients with Type 1 and Type 2 diabetes receiving care at a single primary care facility between 2020 and 2024. We examined the associations between receiving a CGM prescription and demographic characteristics, health factors, de‐identified physician information, and insurance status. We conducted u...

Articles
Mkuu R, Rahman P, Rivero-Mendoza D, Donahoo WT, Shenkman E, Ojo D, Lamas MR•
PubMed

Clopidogrel-Induced Insulin Autoimmune Syndrome: Efficacy of Glucocorticoid Therapy and Continuous Glucose Monitoring.

Introduction Insulin autoimmune syndrome (IAS) is a rare cause of spontaneous hyperinsulinemic hypoglycemia characterized by elevated insulin autoantibody (IAA). Over half of IAS cases involve exposure to sulfhydryl group-containing medications or their active metabolites, with clopidogrel being an uncommon trigger. We report a case of clopidogrel-induced IAS (CIAS) treated with glucocorticoid and managed by continuous glucose monitoring (CGM) during follow-up. Case Report A 77-year-old man d...

Articles
Luo L, Xiong X, Ran J•
PubMed

Continuous Interstitial Glucose Monitoring through a Long-Term Subcutaneous Implantable Sensor during Pregnancy in Type 1 Diabetes: A Two- Patient Case Report.

Introduction Optimal glycaemic control is crucial during pregnancy in women with type 1 diabetes mellitus (T1D). Current guidelines, based on positive data from the CONCEPTT (Continuous Glucose Monitoring in Pregnant Women With Type 1 Diabetes Trial), on maternal glycaemic control and fetal outcomes, recommend offering real-time Continuous Glucose Monitoring (rt-CGM) as a standard method in all pregnancies of women with type 1 diabetes (T1D). Case Presentation In these two clinical cases, we...

Articles
Nazarena B, Veronica R, Alessia G, Antea C, Federica M, Walter V, Emanuela O, Carlo BA•
PubMed

Hybrid Deep Learning Framework for Continuous Blood Glucose Monitoring and Gestational Diabetes Risk Prediction.

Gestational diabetes mellitus (GDM) affects almost 10%-12% of pregnancies worldwide, threatening maternal and fetal life. Continuous glucose monitoring (CGM) forms the backbone of managing GDM, and the current methodologies largely disregard physiological and behavioral factors, thereby greatly reducing accuracy and clinical interpretability. Methods A hybrid deep learning framework was developed by fusing CGM with multi-sensing modality data, including heart rate, activity levels, sleep patte...

Articles
Chanumolu KK, Nagamani GM, Hemalatha GM•
PubMed

Machine Learning and ECG-Derived Biomarkers for Objective Pain Assessment: An Explainable AI Approach Toward Precision Pain Management.

Background Pain assessment disparities across demographic groups pose a significant healthcare challenge, with women, elderly patients, and racial minorities frequently experiencing inadequate treatment. Current pain evaluation relies predominantly on subjective self‐reporting scales, which lack objective physiological biomarkers and can be influenced by communication barriers and provider bias, limiting their effectiveness for equitable and precise pain measurement. Objectives This study inv...

Articles
Sabbadini R, Italiano GF•
PubMed

Remote ECG monitoring as a diagnostic tool for therapeutic strategies after transcatheter aortic valve replacement: rationale and design of the DRAGON-TAVI randomized trial.

Background Severe aortic valve stenosis (AS) is the most common valvular heart disease, and the aging population causes the prevalence of AS to increase each decade [1, 2]. Transcatheter aortic valve implantation (TAVI) is an emerging therapeutic approach for patients with this condition, primarily for those at high surgical risk, but it is increasingly used in a broader group of patients with AS [3, 4]. The TAVI procedure carries a risk of serious complications, such as stroke, life-threateni...

Articles
Lis P, Koźlik M, Chamera M, Kułach A, Smolka G, Smolarek M, Orszulak M, Mizia-Stec K, Szydło K, Gołba K, Gładysz-Wańha S, Kuźma Ł, Morkisz Ł, Gocoł R, Hudziak D, D'Ascenzo F, de Ferrari GM, Lip GYH, Wojakowski W, Wita K, Wańha W•
PubMed

Assessing ECG Findings in Pediatric COVID-19 Patients: A Comprehensive Analysis.

Introduction COVID-19 can be associated with varying degrees of cardiac involvement in children, such that myocardial damage can be caused directly by the COVID-19 virus itself or systemic inflammation caused by the infection. The present study was conducted with the aim of evaluating ECG findings in children with COVID-19. Methods This is a prospective cross-sectional study that was conducted by census method on 764 children with COVID-19 in hospitals related to Mashhad University of Medical...

Articles
Naghibi M, Ghiasi SS, Raesi R, Rahimpour F•