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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,921–1,932 of 2,098 articles

PubMed

Exploring the Impact of Extended Amino Acid Supplementation on Body Composition and Psychopathology in Patients with Eating Disorders Undergoing Psycho-Nutritional Rehabilitation.

Background Eating disorders are frequently linked to protein-energy malnutrition, resulting from chronic energy intake reduction, and leading to reduced body weight and altered body composition. A nutritional approach based on the supplementation with a mixture of essential amino acids has proven effective in conditions characterized by reduced dietary intake and increased degradation of endogenous proteins and might also contribute to correct the amino acid deficiency possibly involved in the...

Articles
Napolillo M, Ragione LD, De Iaco G, Mococci T, Sacco R, Marucci S•
PubMed

Blood Pressure Management in Dialysis: A Comparative Review of Hemodialysis and Peritoneal Dialysis.

Hypertension is a major challenge in patients with end-stage kidney disease (ESKD) undergoing dialysis, contributing to increased cardiovascular morbidity and mortality. Both hemodialysis (HD) and peritoneal dialysis (PD) serve as renal replacement therapies, yet their effectiveness in blood pressure (BP) control remains a subject of ongoing debate. Emerging evidence suggests that PD may offer better BP regulation than HD due to continuous ultrafiltration, superior sodium removal, and the preser...

Articles
Jonny J, Pranidya NP, Sugiharta AJ•
PubMed

Early-Life Predictors of Obesity and High Blood Pressure Comorbidity at Midlife: Findings From the 1958 National Child Development Study (NCDS).

Background Early‐life exposures can increase the risk of both obesity and high blood pressure in adulthood. In this paper, we identify exposures across five pre‐hypothesised childhood domains, explore them as predictors of obesity and high blood pressure comorbidity using the 1958 National Child Development Study (NCDS), and discuss these results in comparison to a similar approach using another birth cohort (1970 British Cohort Study (BCS70)). Methods The analytical sample included 9150 part...

Articles
Stannard S, Owen RK, Berrington A, Ziauddeen N, Fraser SDS, Paranjothy S, Hoyle RJ, Alwan NA•
PubMed

Geographic variation in proportions meeting the waist circumference criterion and having elevated hemoglobin A1c among Specific Health Checkup examinees in Japan: an ecological analysis of the 10th NDB Open Data.

Background Publicly available aggregate health data can support regional surveillance of cardiometabolic risk, but analyses must address aggregation, ecological inference, and cell suppression or unavailability. Waist circumference and body mass index (BMI) capture related but distinct aspects of adiposity. We evaluated the usefulness and limitations of selected 10th National Database (NDB) Open Data indicators for prefecture-level cardiometabolic surveillance among Specific Health Checkup exam...

Articles
Nakashima H, Kamihara T, Omura T•
PubMed

Effectiveness of Individualized Nursing in Perioperative Management of Patients With Obstructive Sleep Apnea: A Retrospective Cohort Study.

Background Patients with obstructive sleep apnea (OSA) are at increased risk of perioperative complications, such as hypoxemia, respiratory depression, and airway obstruction. This study aims to evaluate the effectiveness of individualized nursing in the perioperative management of patients with OSA. Methods We retrospectively analyzed 107 patients with OSA undergoing elective surgery between January 2023 and January 2025, who were allocated to a conventional group (n = 55) or an individualiz...

Articles
Lin Q, Yang Y, Huang C, Huang D, Fang C•
PubMed

SDANN May Be Used as a Screening Factor of Obstructive Sleep Apnea in Adult Individuals.

Background Obstructive sleep apnea (OSA) is a common disease and can be diagnosed with polysomnography (PSG). However, it is limited and has a long waiting time. This study is aimed at evaluating if HRV can be a screening tool for OSA in a real‐world setting. Methods This was a prospective study that enrolled adult patients aged 18 years or older who were suspected of OSA and underwent both PSG and HRV tests. A stepwise multivariable logistic regression analysis was executed to identify predi...

Articles
Sonsuwan N, Charoenwaree C, Chattipakorn N, Sawanyawisuth K•
PubMed

Continuous Positive Airway Pressure Effects on Pulmonary Hemodynamics and Left Ventricular Function in Obstructive Sleep Apnea and Obesity Hypoventilation Syndrome: A Systematic Review and Meta-Analysis.

Background Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are strongly linked to pulmonary hypertension and left ventricular abnormalities, driving cardiovascular issues. OHS, with daytime hypercapnia, affects 10%–20% of OSA patients. Continuous positive airway pressure (CPAP) is the first‐line therapy, but its cardiac effects are inconsistent. Methods We conducted a systematic review and meta‐analysis adhering to the PRISMA 2020 statement. Risk of bias was assessed...

Articles
Li J, Zhao J, Pang PP, Zhai WJ, Wang YK, Zhang XY, Wei YQ•
PubMed

Association of Lactate-to-Albumin Ratio With 28-Day Mortality in Critically Ill Patients With Obstructive Sleep Apnea: A Retrospective Cohort Study Based on the MIMIC-IV Database.

Background Obstructive sleep apnea (OSA) is not uncommon among critically ill patients, especially in those with acute hypercapnic respiratory failure. Its high mortality rate remains a major challenge in the intensive care setting. The frequent apnea and respiratory failure during sleep in OSA patients, along with the intermittent hypoxemia caused by it, are accompanied by a series of systemic pathological and physiological changes. Metabolic imbalance is a key characteristic of the underlying...

Articles
Zhou J, Chi C, Yu F, Wu J, Lou H•
PubMed

Diet and physical activity behaviors among women with polycystic ovary syndrome (PCOS): Are they different from healthy women?

Objective To investigate the diet and physical activity habits among women with polycystic ovary syndrome (PCOS) and compare them with age and BMI matched controls. Methods This cross-sectional cohort study included 90 women with PCOS from a diverse population representing various socioeconomic backgrounds in both urban and rural areas. Ninety women with PCOS, diagnosed according to Rotterdam criteria, were matched for age and BMI with 270 healthy women from the same community who served as a...

Articles
Kamboj S, Arora T, Amlin D, Jyoti A, Ahuja G, Banerjee S, Kutum R, Malhotra N•
PubMed

Comparative Outcomes of Letrozole Versus Clomiphene Citrate for Ovulation Induction in Patients With PCOS: Systematic Review and Meta-Analysis.

Objective This study aimed to synthesize available high-quality randomized controlled trials (RCTs) comparing reproductive outcomes between letrozole (LE) and clomiphene citrate (CC) for ovulation induction in women with PCOS. Methods Following PRISMA guidelines, this review was registered in PROSPERO (CRD420251013416). A comprehensive search was conducted in PubMed, Cochrane Library, Elsevier, the National Library of Medicine, and Google Scholar up to March 2025. A total of 32 RCTs were incl...

Articles
Miller KAR, Pinheiro GM•
PubMed

Assessment of Sonographic Ovarian Volume as an Potential Predictor of Polycystic Ovarian Syndrome (PCOS): A Hospital-Based Cross-Sectional Study.

Introduction Polycystic ovarian syndrome (PCOS) is a prevalent endocrine and metabolic disorder commonly associated with obesity and reproductive morbidities. The relationship between ovarian volume and BMI as well as ovarian morphology was therefore examined in this study to assess whether sonographic ovarian volume can serve as a supportive parameter in predicting PCOS in clinical practice. Methods A hospital-based cross-sectional study of 100 women aged 20–40 years was conducted at the Uni...

Articles
Ali B, Hadadi I, Adam M, Faqihi WA, Sayed M, Alotaibi SA, Gareeballah A, England A•
PubMed

Living with PCOS: A Narrative of its Biology, Diagnosis, and Evolving Treatment.

Introduction Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hyperandrogenism, ovarian dysfunction, and metabolic abnormalities. It affects between 4% and 21% of females of fertile age. The present review provides a comprehensive analysis of PCOS, covering pathophysiology, diagnostic criteria, prevalence, biochemical markers, and demographic influences. It examines genetic, hormonal, and lifestyle variables, contributing to the conditions, highlighting ethnic d...

Articles
Shams S, Jawaid S, Rai N, Kala K, Choudhary A, Neelofar N, Anwar F•