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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,981–1,992 of 2,098 articles

PubMed

The Association between Remnant Cholesterol Levels and Computed Tomography-based Low Bone Mass, Low Muscle Mass, and Osteosarcopenia in Older Adults.

Objective The associations between remnant cholesterol (RC) and low bone mass and sarcopenia have not been well studied. This study aimed to demonstrate the link between serum RC and the prevalence of low bone mass, low muscle mass, and osteosarcopenia in older adults. Methods This retrospective study involved 1995 individuals aged 50 and above who received CT scans for lung cancer screening from 2016 to 2020. Remnant cholesterol (RC) was calculated as follows: total cholesterol (TC) - (low-d...

Articles
Wang R, Wang Y, Liu J, Wei Z, Tang H, Chen X•
PubMed

Feasibility of Predicting the Triglyceride/High-Density Lipoprotein Cholesterol Ratio using Spectral Imaging with a Multi-Material Decomposition Technique on Fast kVp-Switching Dual-Energy CT.

Introduction/Background Non-alcoholic fatty liver disease (NAFLD) is closely associated with increased cardiovascular risk, and the triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is a reliable predictor of cardiometabolic disorders. Dual-energy CT with Multi-Material Decomposition (MMD) enables non-invasive quantification of liver Fat Fraction (FF), but its value in predicting TG/HDL-C ratio remains unexplored. To investigate the correlation between the triglyceride/high-den...

Articles
Xie A, Wang C, Huang S, Zhang J, Zhu L, Zhou J•
PubMed

The Effects of Neonatal Zingerone Administration and Adolescent Alcohol Exposure on Bone Health Markers and Morphometry in Male Sprague-Dawley Rats.

Objective Neonatal interventions influence long‐term developmental outcomes, with excessive alcohol consumption impairing metabolism and bone health. Zingerone, a natural antioxidant, may possess health benefits against alcohol‐induced oxidative damage and inflammation, promoting bone health. This study investigates the effects of zingerone on markers of bone turnover and morphometry in neonatal rats subjected to alcohol exposure during critical developmental stages. Methods Ten‐day‐old male...

Articles
De Vos B, Asiedu B, Joubert AM, Kasonga AE, Nyakudya TT•
PubMed

Selenium Enhances Osteogenic Differentiation and Mineralization in Human Osteoblasts: Implications for Bone Health and Metabolism.

Introduction Sodium Selenite (NaSe) is a molecule with various biological activities. Bone fractures and osteoporotic diseases are increasingly common health issues, prompting the search for alternative treatments. Therefore, the purpose of this study was to examine the antioxidant and osteogenic properties of NaSe. Methods The experiments were conducted using the hFOB1.19 osteoblast cell line. The MTT assay was used to assess the effects of NaSe on cell viability, while cytotoxicity was eval...

Articles
Sahin E, Arafat M, Koparal AT•
PubMed

The Burden, Risk Factor Analysis, and Prediction of Low Back Pain in China From 1990 to 2021.

Introduction The burden of low back pain (LBP) in China poses a substantial public health challenge. This study aimed to analyze longitudinal trends in the burden of LBP and its associated risk factors based on data from the Global Burden of Disease (GBD) 2021 study and to project future trends. Methods Epidemiological data for LBP in China and globally were retrieved from the GBD 2021 database. Disease burden was characterized using summary tables and age‐dependent line graphs. Joinpoint reg...

Articles
Lin A, Ma Y, Zhang C, Yang W, Han S, Zhang H, Liu Z, Tang S, Gong W, Ma X•
PubMed

Comparing VR-Based Exercises and Routine Physical Therapy Effects on Pain, Kinesiophobia, and Functional Abilities in Non-Specific Chronic Low Back Pain Patients "A Randomized Clinical Trial".

Objectives: To compare the effects of Virtual Reality (VR)-based exercises and routine physical therapy on pain, kinesiophobia, and functional abilities in patients with Non-Specific Chronic Low Back Pain (NSCLBP). Methods: Twenty-eight participants aged 20 to 55 were included and randomly assigned to two groups, ensuring single blinding. Both groups received routine physical therapy, which included transcutaneous electrical nerve stimulation (TENS), ultrasound therapy, and infrared light, al...

Articles
Khalifeh F, Karimi N, Mohammadi S, Azarsa MH, Hosseinzade S, Behzadipour S, Masoudi P•
PubMed

Application of operant demand in autism and developmental disabilities: An updated review (2017-2025).

Abstract Operant demand within behavioral economics provides a quantitative framework for evaluating reinforcer efficacy in applied research involving individuals with autism and those with related developmental disabilities. This systematic review extended the work of Gilroy, Kaplan, and Leader (2018) by examining applied operant demand research published between March 2017 and December 2025. Following PRISMA guidelines, 30 articles (31 experiments; 307 participants) were identified and coded...

Articles
Kim JY, Shawler L, Gilroy S•
PubMed

Relationship between BMI-SDS trajectories and childhood asthma: a prospective cohort study from the Japan Environment and Children's Study.

Background The association between obesity and asthma in children has been reported. However, despite its clinical and public health significance, the relationship between longitudinal body mass index standard deviation score (BMI-SDS) trajectories in early life and development of childhood asthma in Japan remains to be elucidated. Methods This study used fixed data on 11,433 parent-child pairs from the Japan Environment and Children’s Study, an ongoing national birth cohort study. Informatio...

Articles
Akaike S, Sakuragi T, Ishitsuka K, Suga R, Shimizu K, Shimizu K, Tomioka H, Yatera K, Yoshino K, Fukano R, Mine Y, Ochiai M, Morokuma S, Hamada N, Tsuji M, Japan Environment and Children’s Study (JECS) Group•
PubMed

Expression Profile of the IL-17 Receptor Family on Peripheral B Lymphocytes in Rheumatoid Arthritis.

B cells are key contributors to the immunopathogenesis of rheumatoid arthritis (RA), yet the expression profile of interleukin‐17 (IL‐17) receptors on human B cells remains incompletely defined. We analyzed the surface expression of IL‐17RA–IL‐17RE on peripheral CD19+ B cells from 42 patients with RA and 20 healthy controls (HC) using flow cytometry. Receptor‐positive cell frequency and mean fluorescence intensity (MFI) were evaluated, and disease activity was assessed using the Disease Activity...

Articles
Fernando CGC, Sonia SF, Jorge HB, Francisco MVJ, Omar GM, Iván LP, Javier MNJ•
PubMed

Research Advances in Targeted Modulation of Macrophage M1/M2 Polarization for the Treatment of Rheumatoid Arthritis.

Rheumatoid arthritis (RA) is a disease of the immune system that leads to continuous synovial inflammation and the progressive breakdown of joints. As essential effector cells in innate immunity, macrophages can become either pro‐inflammatory M1 or anti‐inflammatory M2 phenotypes, playing a critical role in RA pathogenesis. A marked M1/M2 polarization imbalance exists in the synovial microenvironment of RA, in which excessive activation and accumulation of M1 macrophages serve as a key hub drivi...

Articles
Zuo H, Fan E, Zeng L, Hu J, Sang J, Hao F•
PubMed

The Efficacy of Cryotherapy in Reducing Pain and Anxiety During Venipuncture: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background Cold therapy, or cryotherapy, is the application of low temperature to reduce pain and swelling, and it is used widely in routine practice to ease the pain and anxiety of venipuncture. This systematic review and meta‐analysis evaluated its effect on venipuncture pain and anxiety, together with postprocedure heart rate. Methods This systematic review and meta‐analysis was registered on PROSPERO and included randomized controlled trials (RCTs) of cryotherapy during venipuncture, with...

Articles
Shams M, Ahmed A, Shafi N, Anjum HM, Firdous J, Islam N, Sajid HMM, Fatima M, Abid MA, Rezk ZH•
PubMed

Identification of Yersinia Species in Raw Chicken Meat in Tehran Retail Stores and Determination of Their Antibiotic Resistance Pattern.

Introduction: Yersinia constitutes one of the predominant bacterial agents implicated in foodborne illnesses. The objective of this investigation is to ascertain the presence of Yersinia species in raw chicken meat procured from retail establishments in Tehran, alongside an examination of their antibiotic resistance patterns. Materials & Methods: Between April and September 2023, a total of 220 chicken meat samples were systematically collected and analyzed for contamination by Yersinia speci...

Articles
Mohammadi MR, Rajabi Z, Soltan Dallal MM•