Gallstone Solubilizing Agents

Gallstone solubilizing agents, also known as cholelitholytic bile acid therapies, are a specialized therapeutic class of naturally occurring bile acids, primarily including ursodiol and chenodiol Clinically, these agents are utilized for the medical dissolution of small, radiolucent, non-calcified gallstones in patients who are non-surgical candidates, as well as for the prevention of gallstone formation during rapid weight loss Additionally, select agents within this class are indicated for chr...

Gallstone solubilizing agents, also known as cholelitholytic bile acid therapies, are a specialized therapeutic class of naturally occurring bile acids, primarily including ursodiol and chenodiol Clinically, these agents are utilized for the medical dissolution of small, radiolucent, non-calcified gallstones in patients who are non-surgical candidates, as well as for the prevention of gallstone formation during rapid weight loss

They function primarily by decreasing hepatic secretion and synthesis of cholesterol and reducing intestinal cholesterol absorption, which desaturates biliary cholesterol and facilitates the gradual dispersion and dissolution of cholesterol gallstones

They function primarily by decreasing hepatic secretion and synthesis of cholesterol and reducing intestinal cholesterol absorption, which desaturates biliary cholesterol and facilitates the gradual dispersion and dissolution of cholesterol gallstones Additionally, select agents within this class are indicated for chronic cholestatic hepatobiliary conditions, particularly primary biliary cholangitis

They function primarily by decreasing hepatic secretion and synthesis of cholesterol and reducing intestinal cholesterol absorption, which desaturates biliary cholesterol and facilitates the gradual dispersion and dissolution of cholesterol gallstones