Drug class

Gallstone Solubilizing Agents

Gallstone solubilizing agents, also known as cholelitholytic bile acid therapies, are a specialized therapeutic class of naturally occurring bile acids, primarily including ursodiol and chenodiol. Read more about Gallstone Solubilizing Agents

28 drugs in this class 27 manufacturers

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Drugs in Gallstone Solubilizing Agents

Showing 28–28 of 28 drugs

URSOLIGN (ursodiol)

GALLSTONE SOLUBILIZING AGENTS · CHOLELITHIASIS PREVENTION ·+1
PANGEA PHARMACE
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About Gallstone Solubilizing Agents.

Gallstone solubilizing agents, also known as cholelitholytic bile acid therapies, are a specialized therapeutic class of naturally occurring bile acids, primarily including ursodiol and chenodiol.

They function primarily by decreasing hepatic secretion and synthesis of cholesterol and reducing intestinal cholesterol absorption, which desaturates biliary cholesterol and facilitates the gradual dispersion and dissolution of cholesterol gallstones.

Clinically, these agents are utilized for the medical dissolution of small, radiolucent, non-calcified gallstones in patients who are non-surgical candidates, as well as for the prevention of gallstone formation during rapid weight loss.

Additionally, select agents within this class are indicated for chronic cholestatic hepatobiliary conditions, particularly primary biliary cholangitis.