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Drug class

Selective Serotonin 5-HT3 Antagonists

Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone. Read more about Selective Serotonin 5-HT3 Antagonists

115 drugs in this class 80 manufacturers

Related classes & indications

Proton Pump InhibitorsGastrointestinal · 219 prescription drugs Histamine-2 Receptor Antagonists (H2 Antagonists)Gastrointestinal · 78 prescription drugs Prevention Of Cancer Chemotherapy-Induced Nausea And VomitingTop indication · 268 prescription drugs

Showing 82–90 of 115 drugs

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ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2

DENTON PHARMA I

PALONOSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1

MEITHEAL PHARMA

ONDANSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2

APHENA PHARMA S

ONDANSETRON ODT (ondansetron)

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2

LIFSA DRUGS LLC

ONDANSETRON HCL (ondansetron HCl/PF)

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1

CIVICA, INC.

ONDANSETRON ODT (ondansetron)

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2

ENOVACHEM MANUF

ONDANSETRON ODT (ondansetron)

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+2

ADVANCED RX PHA

PALONOSETRON HCL

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1

AVENACY, INC

POSFREA (palonosetron HCl)

ANTIEMETIC · PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING ·+1

AVYXA PHARMA, L

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About Selective Serotonin 5-HT3 Antagonists.

Selective serotonin 5-HT3 antagonists are a therapeutic class of medications that competitively inhibit type 3 serotonin (5-HT3) receptors located peripherally on gastrointestinal vagal afferents and centrally within the chemoreceptor trigger zone.

By blocking serotonin-mediated emetic signaling, these agents primarily serve as potent antiemetics to prevent and manage nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgical procedures.

Additionally, specific agents in this class are utilized in gastroenterology to treat severe diarrhea-predominant irritable bowel syndrome by reducing colonic motility and visceral sensitivity.