Indication
Adjuvant therapy following surgical resection of Kit (CD117) positive gastrointestinal stromal tumor
Kit (CD117)-positive gastrointestinal stromal tumors are mesenchymal neoplasms arising from the interstitial cells of Cajal within the digestive tract, most commonly in the stomach or small intestine. Read more about Adjuvant therapy following surgical resection of Kit (CD117) positive gastrointestinal stromal tumor
28 drugs 27 manufacturers
Drugs that treat it
Common Adjuvant therapy following surgical resection of Kit (CD117) positive gastrointestinal stromal tumor therapies.
IMATINIB MESYLATE
IMATINIB MESYLATE
IMKELDI (imatinib mesylate)
IMATINIB MESYLATE
IMATINIB MESYLATE
IMATINIB MESYLATE
GLEEVEC (imatinib mesylate)
IMATINIB MESYLATE
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Coming soonAbout Adjuvant therapy following surgical resection of Kit (CD117) positive gastrointestinal stromal tumor.
Kit (CD117)-positive gastrointestinal stromal tumors are mesenchymal neoplasms arising from the interstitial cells of Cajal within the digestive tract, most commonly in the stomach or small intestine.
Pathophysiologically, these tumors are characterized by cell-surface expression of the CD117 antigen, typically driven by activating mutations in the *KIT* proto-oncogene receptor tyrosine kinase that promote uncontrolled cellular proliferation.
In this post-surgical clinical state, patients who have undergone complete gross surgical resection of the primary tumor face a variable risk of disease recurrence depending on tumor size, mitotic rate, location, or tumor rupture.
Adjuvant therapy is indicated in this setting to eradicate residual micrometastatic disease and reduce the risk of relapse.
- ajmc.com
Kit (CD117)-positive gastrointestinal stromal tumors are mesenchymal neoplasms arising from the interstitial cells of Cajal within the digestive tract, most commonly in the stomach or small intestine Pathophysiologically, these tumors are characterized by cell-surface expression of the CD117 antigen, typically driven by activating mutations in the *KIT* proto-oncogene receptor tyrosine kinase that promote uncontrolled cellular proliferation
- nih.gov
Kit (CD117)-positive gastrointestinal stromal tumors are mesenchymal neoplasms arising from the interstitial cells of Cajal within the digestive tract, most commonly in the stomach or small intestine
- prnewswire.com
Pathophysiologically, these tumors are characterized by cell-surface expression of the CD117 antigen, typically driven by activating mutations in the *KIT* proto-oncogene receptor tyrosine kinase that promote uncontrolled cellular proliferation
- nih.gov
Pathophysiologically, these tumors are characterized by cell-surface expression of the CD117 antigen, typically driven by activating mutations in the *KIT* proto-oncogene receptor tyrosine kinase that promote uncontrolled cellular proliferation In this post-surgical clinical state, patients who have undergone complete gross surgical resection of the primary tumor face a variable risk of disease recurrence depending on tumor size, mitotic rate, location, or tumor rupture Adjuvant therapy is indic...
- fda.gov
In this post-surgical clinical state, patients who have undergone complete gross surgical resection of the primary tumor face a variable risk of disease recurrence depending on tumor size, mitotic rate, location, or tumor rupture
- ascopost.com
In this post-surgical clinical state, patients who have undergone complete gross surgical resection of the primary tumor face a variable risk of disease recurrence depending on tumor size, mitotic rate, location, or tumor rupture
- liferaftgroup.org
Adjuvant therapy is indicated in this setting to eradicate residual micrometastatic disease and reduce the risk of relapse
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