Hyperkeratosis

Hyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules Pathophysiologically, it arises as a protective physiologic response to chronic friction, or secondary to underlying inflammato...

Hyperkeratosis refers to the abnormal thickening of the stratum corneum, the outermost layer of the epidermis, typically resulting from excess production of keratin or retention of corneocytes

It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules

It primarily affects the integumentary system across diverse patient populations and can manifest as localized or generalized rough, scaly, thickened plaques, calluses, or papules

Pathophysiologically, it arises as a protective physiologic response to chronic friction, or secondary to underlying inflammatory dermatoses, genetic disorders of cornification, or premalignant alterations