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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,753–1,764 of 2,098 articles

PLOS

Concurrent measurement of working memory and inhibitory control and their correlations with autistic and ADHD traits in the general population

Executive function can be defined as the combination of goal representation in working memory and the inhibition of goal-irrelevant responses. This paper comprises two complementary studies that assess these core components of executive function orthogonally and examine their correlation with ASD and ADHD traits in the general population. Both studies utilized a paradigm with two tasks, each assessing working memory and one type of inhibitory control concurrently: the modified flanker task, whic...

Articles
Yasamin Rahmati, Christopher Jarrold•
PLOS

Evaluation of a home pharmaceutical care service model for home-based patients receiving anticoagulation therapy within county-level medical community

Objective: To establish a systematic, standardized, and operational model of home pharmaceutical care for patients with anticoagulant treatment in county-level medical community. Methods: A home pharmaceutical care service team was constituted by pharmacists and physicians from the county-level medical community. A home-based pharmaceutical care survey was conducted for patients with long-term oral anticoagulants (VKAs, rivaroxaban, dabigatran and apixaban). The patients’ awareness and adherence...

Articles
JianAo Song, Bin Chen, Jinhui Sun, KaiZhan Zhuang•
PubMed

Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition.

Purpose Emerging evidence implicates ferroptosis in trabecular meshwork (TM) injury during glaucoma pathogenesis. This study aims to systematically characterize ferroptosis-related gene signatures in primary open-angle glaucoma (POAG) and identify small-molecule therapeutics targeting this mechanism. Methods We performed Mendelian randomization (MR) analysis of East Asian genome-wide association study data to assess causal relationships between blood metals and POAG. Ferroptosis-related indic...

Articles
Zhou X, Li Z, Zhang X, Xu J, Wu P, Zhu W, Ji D, Duan X•
PubMed

Comparing optical coherence tomography angiography biomarker for primary open-angle glaucoma and normal tension glaucoma progression in different stage.

PURPOSE: To compare peripapillary and parafoveal microvasculature between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) at different disease stages using optical coherence tomography angiography (OCTA). MATERIALS AND METHODS: This retrospective study classified eyes into early, moderate, or severe visual field defect based on Hodapp-Parrish-Anderson criteria. OCTA was used to assess radial peripapillary capillaries (RPCs), retinal nerve fiber layer (RNFL), parafoveal ve...

Articles
Kuo YK, Chan YH, Huang TE, Liu CF, Lai CC, Chuang LH•
PubMed

Blood levels of brain-derived neurotrophic factor (BDNF) in psoriasis: a systematic review and meta-analysis.

Introduction Psoriasis is a chronic inflammatory skin condition affecting 0.1–1.5% of the global population. The condition is linked to impaired quality of life and increased morbidity. Brain-derived neurotrophic factor (BDNF) is a neurotrophin associated with neuronal development and synaptic plasticity; its dysregulation has been implicated in the pathogenesis of psoriasis. This study systematically reviews and analyzes the relationship between BDNF levels and psoriasis. Methods A systemati...

Articles
Sarasyabi MS, Seighali N, Abdolmaleki M, Shobeiri P, Movahed MR, Bozorgnia F, Maleki S•
PubMed

Iatrogenic Upper Gastrointestinal Bleeding Following Nasogastric Tube Insertion in a Patient with Pemphigus Vulgaris.

Dear Editor, Pemphigus vulgaris (PV) mainly affects the oral mucosa and skin; esophageal involvement has been controversial for many years.1 The first site of PV is usually the oral mucosa, and erosions seen in any area of the mouth and eroded areas seen in the vermilion of the lips are quite typical. Bullae easily rupture, causing painful erosions with epithelial debris at the edges. Nikolsky’s sign (the formation of a bullae by mechanical pressure applied to the edge of the bullae, normal ski...

Articles
Ketenci YB, Çakır A, Yılmaz GA, Avcıoğlu U, Demiröz H, Akca M•
PubMed

Resting-state EEG markers associated with violence risk in patients with major depressive disorder.

Background Growing studies have reported an elevated risk of violence in patients with depression, yet the neurobiological underpinnings remain poorly understood. The present study explored the resting-state electroencephalogram (EEG) features in major depressive disorder (MDD) patients with violent offenses to identify potential neurological markers for violence prediction and intervention. Methods Twenty-nine MDD patients who committed violent offenses (violent depression [VD] group), 27 MD...

Articles
Xie Y, Lu W, Chen J, Tan S, Ma T, Gu Y, Li Y, Li G•
PubMed

Fentanyl and Propofol Versus Fentanyl and Etomidate for the Insertion Conditions of Laryngeal Mask Airway: A Prospective Observational Study.

Background: Laryngeal mask airway (LMA) is often used in short surgeries for its easy insertion and minimal invasiveness but successful placement needs reflex suppression and stable vitals. This study compared Fentanyl-Propofol which gives better insertion but may cause hypotension with Fentanyl-Etomidate which maintains hemodynamics but causes more myoclonus. Material and Methods: 60 American Society of Anesthesiologists I–II patients aged 18–60 years were included in this prospective study....

Articles
Pal R, Verma A, Valecha D•
PubMed

Patient-reported improvements from use of IMC-2 alone and IMC-2 and Paxlovid(®) in a Long COVID cohort: a case series.

Introduction Long COVID (LC) is an infection-associated chronic condition and illness (IACCI) with no currently approved treatments. In order to address SARS-CoV-2 persistence and herpesvirus reactivation, which have been implicated as drivers of LC, sustained use of antiviral combinations may be useful in treating patients with the illness. Methods A convenience sample of patients undergoing an extended course of antiviral therapy was studied. Patients received either 120 days of IMC-2 only...

Articles
Pridgen WL, Putrino D•
PubMed

Deep Venous Thrombosis Within Two Weeks of Initiating Oral Semaglutide (Rybelsus): A Case Report.

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasingly prescribed for type 2 diabetes mellitus and weight management, with growing off-label use in young adults. While GLP-1RAs are generally well tolerated, emerging evidence suggests potential associations with thromboembolic events. We report the case of a 16-year-old male with mild conventional risk factors for thrombosis [overweight body mass index (BMI) and prolonged sedentary behavior] who developed acute left lower extremit...

Articles
Alsermani M, Ali Alkahmous B, Alhutayrashi AA, Alshalhoob FS, Abulrahman Almosaiteer S, Aljubayri E, Saleh Alwabel A, Sermani A•
PubMed

Erratum: Correction of Text in the Article "Complications of Nasopharyngeal Swabs and Safe Procedures for COVID-19 Testing Based on Anatomical Knowledge".

To the Editor: The authors regret that there were errors in Text in the above article. Due to the omission of the word “never”, two sentences were inadvertently written in a way that could be misinterpreted as recommending forceful insertion or movement during nasopharyngeal swab procedures. This notice corrects the errors as follows. Content of correction: 1) Abstract (third to last sentence) Original sentence: “Forceful insertion should be attempted, and alternative examinations should b...

Articles
Kim DH, Kim D, Moon JW, Chae SW, Rhyu IJ•
PubMed

Enhancing Cleavage Aesthetics in Patients Seeking Breast Augmentation: Surgical Technique and Key Considerations.

Background Hybrid breast augmentation, a combination of silicone implants and autologous fat grafting, is an innovative approach aimed at achieving natural aesthetics. This study evaluates its impact on reducing intermammary distance and improving cleavage aesthetics. Materials and Methods This article and the accompanying videos provide a detailed, step-by-step guide to hybrid breast augmentation using a subfascial inframammary approach, with a predictable and reproducible surgical outcome....

Articles
Gupta R, Rao T, Bansal P, Chaudhury G•